Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer.

Phyllomedusine frogs are an extraordinary source of biologically active peptides. At least 8 families of antimicrobial peptides have been reported in this frog clade, the dermaseptins being the most diverse. By a peptidomic approach, integrating molecular cloning, Edman degradation sequencing and ta...

• Autore principale: Proaño Bolaños, Carolina (author)
• Altri autori: Zhou, Mei (author), Wang, Lei (author), Coloma, Luis A. (author), Chen, Tianbao (author), Shaw, Chris (author)
• Natura: article
• Pubblicazione: 2016
• Soggetti: Antimicrobial peptides; Cruzioseptins; Molecular cloning; Peptidomic; Skin secretions
• Accesso online: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/139; https://doi.org/10.1016/j.jprot.2016.06.017