Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer.

Phyllomedusine frogs are an extraordinary source of biologically active peptides. At least 8 families of antimicrobial peptides have been reported in this frog clade, the dermaseptins being the most diverse. By a peptidomic approach, integrating molecular cloning, Edman degradation sequencing and ta...

• Autor principal: Proaño Bolaños, Carolina (author)
• Outros Autores: Zhou, Mei (author), Wang, Lei (author), Coloma, Luis A. (author), Chen, Tianbao (author), Shaw, Chris (author)
• Formato: article
• Publicado em: 2016
• Assuntos: Antimicrobial peptides; Cruzioseptins; Molecular cloning; Peptidomic; Skin secretions
• Acesso em linha: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/139; https://doi.org/10.1016/j.jprot.2016.06.017