One-Pot Peptide Ligation – Oxidative Cyclization Protocol for the Preparation of Short/Medium Size Disulfide Cyclopeptides

Native chemical ligation (NCL) employing the N-methylbenzimidazolinone (MeNbz) linker readily provided the linear precursor of a 16-mer peptide that is difficult to obtain by stepwise solid-phase peptide synthesis. NCL and the workup conditions were improved toward a protocol that allows for quantitat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Spengler, Jan (author)
Otros Autores: Blanco Canosa, Juan B. (author), Forni, Luciano (author), Albericio, Fernando (author)
Formato: article
Publicado: 2018
Materias:
Acceso en línea:https://doi.org/10.1021/acs.orglett.8b01741
http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/213
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!