One-Pot Peptide Ligation – Oxidative Cyclization Protocol for the Preparation of Short/Medium Size Disulfide Cyclopeptides
Native chemical ligation (NCL) employing the N-methylbenzimidazolinone (MeNbz) linker readily provided the linear precursor of a 16-mer peptide that is difficult to obtain by stepwise solid-phase peptide synthesis. NCL and the workup conditions were improved toward a protocol that allows for quantitat...
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| Other Authors: | , , |
| Format: | article |
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2018
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| Online Access: | https://doi.org/10.1021/acs.orglett.8b01741 http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/213 |
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