Susceptibility analysis of mutations that confer resistance to inhibitors of the main protease (Mpro) and RNA-dependent RNA polymerase (RdRp) of the SARS-CoV-2 virus

Susceptibility analysis of mutations that confer resistance to inhibitors of the main protease (Mpro) and RNA-dependent RNA polymerase (RdRp) of the SARS-CoV-2 virus

Enormous efforts have been made worldwide to generate therapeutic options to prevent the transmissibility of the SARS-CoV-2 and reduce its replication in humans. Currently, the emergence of new variants of the virus is of great concern because the evolution of the viral genome and the inherent mutat...

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Bibliographic Details
Main Author: Espín-Sánchez, Daysi (author)
Other Authors: Vizuete-Rubio, Carolina (author), Jaramillo-Guapisaca, karen (author), Ramos-Aristimbay, María (author), Sánchez-Vaca, Andrés (author), Chico-Terán, Fernanda (author), Cerda-Mejía, Liliana (author), García, Mario (author)
Format: article
Language:spa
Published: 2022
Subjects:
SARS-CoV-2, Mpro, RdRp, homología, mutaciones, docking.
SARS-CoV-2, Mpro, RdRp, homology, mutations, docking.
Online Access:https://revistas.uta.edu.ec/erevista/index.php/aci/article/view/1845
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https://revistas.uta.edu.ec/erevista/index.php/aci/article/view/1845

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