Xantoastrocitoma pleomórfico
The pleomorphic xantoastrocytoma, due to its extreme rarity, carries high complexity in the histo-pathological diagnosis. The clinical case is presented in a male subject, 40 years old, with a history of sei-zures with late presentation, secondary to atypical meningioma grade II located in the left...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| التنسيق: | article |
| اللغة: | spa |
| منشور في: |
2017
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582 |
| الوسوم: |
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إضافة وسم | الملخص: | The pleomorphic xantoastrocytoma, due to its extreme rarity, carries high complexity in the histo-pathological diagnosis. The clinical case is presented in a male subject, 40 years old, with a history of sei-zures with late presentation, secondary to atypical meningioma grade II located in the left occipital region, resected twice in the course of 6 years. He received full-dose radiation therapy after the second resection. The initial histopathological diagnosis was atypical meningioma grade II. The patient comes to HCAM due to intense holocranial headache and right brachiocrural hemiparesis; In the gadolinium nuclear magnetic resonance studies the growth of a left occipital lesion with perilesional edema that warranted total resec-tion of the lesion through previouscraniectomy was observed. As a macroscopic finding, a violaceous mass is described which infiltrates dura mater lacking a plane of cleavage; The histopathological study details a hypercellular glial neoplasia with diffuse infiltration with intense immunohistochemical reaction for PGAF (glial acidic glial protein), S100 and CD56 in tumor cells, CD34 positive. It was KI67 positive in 3% and P53 weakly positive, compatible with pleomorphicxantoastrocytoma WHO II. |
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