Xantoastrocitoma pleomórfico
The pleomorphic xantoastrocytoma, due to its extreme rarity, carries high complexity in the histo-pathological diagnosis. The clinical case is presented in a male subject, 40 years old, with a history of sei-zures with late presentation, secondary to atypical meningioma grade II located in the left...
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| Lingua: | spa |
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2017
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| Accesso online: | https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582 |
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| author | León, Carlos Alberto |
| author2 | Acosta, José Leonardo Diez, Christian Xavier |
| author2_role | author author |
| author_facet | León, Carlos Alberto Acosta, José Leonardo Diez, Christian Xavier |
| author_role | author |
| collection | Revista Ciencias Médicas |
| dc.creator.none.fl_str_mv | León, Carlos Alberto Acosta, José Leonardo Diez, Christian Xavier |
| dc.date.none.fl_str_mv | 2017-06-01 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582 10.29166/ciencias_medicas.v42i2.1582 |
| dc.language.none.fl_str_mv | spa |
| dc.publisher.none.fl_str_mv | Quito: Universidad Central del Ecuador |
| dc.relation.none.fl_str_mv | https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582/1517 |
| dc.rights.none.fl_str_mv | Derechos de autor 2019 Carlos Alberto León, José Leonardo Acosta, Christian Xavier Diez info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | Revista de la Facultad de Ciencias Médicas (Quito); Vol. 42 No. 2 (2017): Revista de la Facultad de Ciencias Médicas (Quito); 185-188 Revista de la Facultad de Ciencias Médicas (Quito); Vol. 42 Núm. 2 (2017): Revista de la Facultad de Ciencias Médicas (Quito); 185-188 2737-6141 2588-0691 reponame:Revista Ciencias Médicas instname:Universidad Central del Ecuador instacron:UCE |
| dc.subject.none.fl_str_mv | xantoastrocitoma pleomórfico meningioma atípico recidivante xantoma fibroso astrocitoma grado II xanthoastrocytoma pleomorphic atypical recurrent meningioma fibrous xanthoma astrocy-toma grade II |
| dc.title.none.fl_str_mv | Xantoastrocitoma pleomórfico |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artículo evaluado por pares |
| description | The pleomorphic xantoastrocytoma, due to its extreme rarity, carries high complexity in the histo-pathological diagnosis. The clinical case is presented in a male subject, 40 years old, with a history of sei-zures with late presentation, secondary to atypical meningioma grade II located in the left occipital region, resected twice in the course of 6 years. He received full-dose radiation therapy after the second resection. The initial histopathological diagnosis was atypical meningioma grade II. The patient comes to HCAM due to intense holocranial headache and right brachiocrural hemiparesis; In the gadolinium nuclear magnetic resonance studies the growth of a left occipital lesion with perilesional edema that warranted total resec-tion of the lesion through previouscraniectomy was observed. As a macroscopic finding, a violaceous mass is described which infiltrates dura mater lacking a plane of cleavage; The histopathological study details a hypercellular glial neoplasia with diffuse infiltration with intense immunohistochemical reaction for PGAF (glial acidic glial protein), S100 and CD56 in tumor cells, CD34 positive. It was KI67 positive in 3% and P53 weakly positive, compatible with pleomorphicxantoastrocytoma WHO II. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | REVCMED_2a2b6354c55f9c17cef02e3efdf4e5fb |
| identifier_str_mv | 10.29166/ciencias_medicas.v42i2.1582 |
| instacron_str | UCE |
| institution | UCE |
| instname_str | Universidad Central del Ecuador |
| language | spa |
| network_acronym_str | REVCMED |
| network_name_str | Revista Ciencias Médicas |
| oai_identifier_str | oai:revistadigital.uce.edu.ec:article/1582 |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Quito: Universidad Central del Ecuador |
| reponame_str | Revista Ciencias Médicas |
| repository.mail.fl_str_mv | * |
| repository.name.fl_str_mv | Revista Ciencias Médicas - Universidad Central del Ecuador |
| repository_id_str | * |
| rights_invalid_str_mv | Derechos de autor 2019 Carlos Alberto León, José Leonardo Acosta, Christian Xavier Diez |
| spelling | Xantoastrocitoma pleomórficoLeón, Carlos AlbertoAcosta, José LeonardoDiez, Christian Xavierxantoastrocitoma pleomórficomeningioma atípico recidivantexantoma fibrosoastrocitoma grado IIxanthoastrocytoma pleomorphicatypical recurrent meningiomafibrous xanthomaastrocy-toma grade IIThe pleomorphic xantoastrocytoma, due to its extreme rarity, carries high complexity in the histo-pathological diagnosis. The clinical case is presented in a male subject, 40 years old, with a history of sei-zures with late presentation, secondary to atypical meningioma grade II located in the left occipital region, resected twice in the course of 6 years. He received full-dose radiation therapy after the second resection. The initial histopathological diagnosis was atypical meningioma grade II. The patient comes to HCAM due to intense holocranial headache and right brachiocrural hemiparesis; In the gadolinium nuclear magnetic resonance studies the growth of a left occipital lesion with perilesional edema that warranted total resec-tion of the lesion through previouscraniectomy was observed. As a macroscopic finding, a violaceous mass is described which infiltrates dura mater lacking a plane of cleavage; The histopathological study details a hypercellular glial neoplasia with diffuse infiltration with intense immunohistochemical reaction for PGAF (glial acidic glial protein), S100 and CD56 in tumor cells, CD34 positive. It was KI67 positive in 3% and P53 weakly positive, compatible with pleomorphicxantoastrocytoma WHO II.El xantoastrocitoma pleomórfico, por su extrema rareza, conlleva alta complejidad en el diagnóstico histopatológico. Se presenta el caso clínico en un sujeto de sexo masculino, de 40 años, con antecedentes de crisis convulsivas de presentación tardía, secundarias a meningioma atípico grado II localizado enregión occipital izquierda, resecado por dos ocasiones en el transcurso de 6 años. Recibió radioterapia a dosis completa luego de la segunda resección. El diagnóstico histopatológico inicial fue meningioma atípico gra-do II. El paciente acude al HCAM por cefalea holocraneal intensa y hemiparesia braquiocruralderecha; en los estudios de resonancia magnética nuclear con gadolinio se observó el crecimiento de una lesión occipi-tal izquierda con edema perilesional que ameritó resección total de la lesión a través de la craniectomía previa. Como hallazgo macroscópico, se describe una masa violácea que infiltra duramadrecarente de un plano de clivaje; el estudio histopatológico detalla una neoplasia glial hipercelular con infiltración difusa con reacción inmunohistoquímica intensa para PGAF (proteína glial acida fibrilar), S100 y CD56 en células tumorales, CD34 positivo. KI67 positivo en 3% y P53 débilmente positivo, compatiblecon xantoastroci-toma pleomórfico WHO II.Quito: Universidad Central del Ecuador2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtículo evaluado por paresapplication/pdfhttps://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/158210.29166/ciencias_medicas.v42i2.1582Revista de la Facultad de Ciencias Médicas (Quito); Vol. 42 No. 2 (2017): Revista de la Facultad de Ciencias Médicas (Quito); 185-188Revista de la Facultad de Ciencias Médicas (Quito); Vol. 42 Núm. 2 (2017): Revista de la Facultad de Ciencias Médicas (Quito); 185-1882737-61412588-0691reponame:Revista Ciencias Médicasinstname:Universidad Central del Ecuadorinstacron:UCEspahttps://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582/1517Derechos de autor 2019 Carlos Alberto León, José Leonardo Acosta, Christian Xavier Diezinfo:eu-repo/semantics/openAccess2020-01-07T17:55:17Zoai:revistadigital.uce.edu.ec:article/1582Portal de revistashttps://revistadigital.uce.edu.ec/Universidad públicahttps://uce.edu.ec/**Ecuador*2737-61412588-0691opendoar:*2020-01-07T17:55:17Revista Ciencias Médicas - Universidad Central del Ecuadorfalse |
| spellingShingle | Xantoastrocitoma pleomórfico León, Carlos Alberto xantoastrocitoma pleomórfico meningioma atípico recidivante xantoma fibroso astrocitoma grado II xanthoastrocytoma pleomorphic atypical recurrent meningioma fibrous xanthoma astrocy-toma grade II |
| status_str | publishedVersion |
| title | Xantoastrocitoma pleomórfico |
| title_full | Xantoastrocitoma pleomórfico |
| title_fullStr | Xantoastrocitoma pleomórfico |
| title_full_unstemmed | Xantoastrocitoma pleomórfico |
| title_short | Xantoastrocitoma pleomórfico |
| title_sort | Xantoastrocitoma pleomórfico |
| topic | xantoastrocitoma pleomórfico meningioma atípico recidivante xantoma fibroso astrocitoma grado II xanthoastrocytoma pleomorphic atypical recurrent meningioma fibrous xanthoma astrocy-toma grade II |
| url | https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1582 |