Characterization of patients with osteoporosis treated with Vitamin D 100,000 IU monthly. 2020

Introduction: Vitamin D in the skin after sun exposure constitutes precursor and bone anabolic agent that stimulates theactive transport of calcium through the intestinal mucosa. The European Society for Clinical and Economic Aspects of Osteoporosisand Osteoarthritis, recommends that postmenopausal patients with 25 (OH) D levels less than 50 nmol / L receivesupplementation between 800 and 1000 IU daily of vitamin D.Objective: Determine in women with osteoporosis the percentage change of 25 (OH) vitamin D in blood, with the administrationof 100,000 IU of vitamin D caps once a month, as well as safety and degree of satisfaction with the treatment.Subjects and methods: Observational, descriptive and longitudinal study, which included 44 women who received 100,000IU of vitamin D once a month for three months. Pre and Post-treatment laboratory control was performed on a non-probabilisticsubsample of 10 patients.Results: The 70% of cases reported not having comorbidities. The initial value of vitamin D was 23.5±10.1 nmol/l at the endthe average was 27.2±9.6 nmol/l in the subsample. Post-treatment increased Vit D. levels 20.4% in more than 50% of cases,93% of cases did not report adverse events. The adverse events reported were gastro-intestinal, osteo-articular events andheadache. The majority of cases reported being satisfied with the treatment.Conclusion: Treatment was very well tolerated, the majority of cases reported being satisfied with the treatment. Significantpercentage increases of 25 (OH) D were observed in blood after 12 weeks of treatment.

• Hlavní autor: Bucheli Terán, Rubén (author)
• Další autoři: Romero Proaño, Sandro Patricio (author)
• Médium: article
• Jazyk: spa
• Vydáno: 2020
• Témata: Vitamina D, osteoporosis, caracterización
• On-line přístup: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/2672