Review about graphene- based biosensors for detection of SARS-COV-2
Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of informat...
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2021
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| author | Mena-Lizano, Daniel |
| author2 | Acurio, Eliana Pachacama-Choca, Richard Tubón-Usca, Gabriela |
| author2_role | author author author |
| author_facet | Mena-Lizano, Daniel Acurio, Eliana Pachacama-Choca, Richard Tubón-Usca, Gabriela |
| author_role | author |
| collection | Revista FIGEMPA: Investigación y Desarrollo |
| dc.creator.none.fl_str_mv | Mena-Lizano, Daniel Acurio, Eliana Pachacama-Choca, Richard Tubón-Usca, Gabriela |
| dc.date.none.fl_str_mv | 2021-12-16 |
| dc.format.none.fl_str_mv | application/pdf text/xml application/zip |
| dc.identifier.none.fl_str_mv | https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519 10.29166/revfig.v12i2.3519 |
| dc.language.none.fl_str_mv | spa |
| dc.publisher.none.fl_str_mv | Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador |
| dc.relation.none.fl_str_mv | https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4305 https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4348 https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4349 |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | FIGEMPA: Investigación y Desarrollo; Vol. 12 No. 2 (2021): Rediscover; 70-84 FIGEMPA: Investigación y Desarrollo; Vol. 12 Núm. 2 (2021): Reencuentro; 70-84 2602-8484 1390-7042 10.29166/revfig.v12i2 reponame:Revista FIGEMPA: Investigación y Desarrollo instname:Universidad Central del Ecuador instacron:UCE |
| dc.subject.none.fl_str_mv | Biosensores covid-19 detección grafeno SARS-COV-2 Biosensors covid-19 detection graphene SARS-COV-2 |
| dc.title.none.fl_str_mv | Review about graphene- based biosensors for detection of SARS-COV-2 Revisión acerca de biosensores basados en grafeno para la detección del SARSCOV- 2. |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of information on this type of biosensors published in high-impact journals in recent years. For the development of the study, parameters such as detection time, detection limit, type of sensor, proteins that the biosensor detects, type of graphene, and cost were chosen to verify its effectiveness. The analyzed results demonstrate that most biosensors functionalizing the antibody of S, N protein or recombination of both, and some biosensors allow the detection of up to 4 types of proteins (C-reactive protein, IgG, IgM, and nucleapside). Several of the analyzed studies show a specific sequence detection of the virus and a low limit of detection (LOD) ranging from 0.1 fg/mL to 1 fg/mL, which allows detecting SARS-CoV-2 at low concentrations. In conclusion, the analysis indicates a feasible option for the implementation of graphene-based biosensors as an alternative to traditional test. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | REVFIGEMPA_2c19406a9f662ab070acaaf07533c092 |
| identifier_str_mv | 10.29166/revfig.v12i2.3519 |
| instacron_str | UCE |
| institution | UCE |
| instname_str | Universidad Central del Ecuador |
| language | spa |
| network_acronym_str | REVFIGEMPA |
| network_name_str | Revista FIGEMPA: Investigación y Desarrollo |
| oai_identifier_str | oai:revistadigital.uce.edu.ec:article/3519 |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador |
| reponame_str | Revista FIGEMPA: Investigación y Desarrollo |
| repository.mail.fl_str_mv | * |
| repository.name.fl_str_mv | Revista FIGEMPA: Investigación y Desarrollo - Universidad Central del Ecuador |
| repository_id_str | 0 |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc/4.0 |
| spelling | Review about graphene- based biosensors for detection of SARS-COV-2Revisión acerca de biosensores basados en grafeno para la detección del SARSCOV- 2.Mena-Lizano, DanielAcurio, ElianaPachacama-Choca, RichardTubón-Usca, GabrielaBiosensorescovid-19deteccióngrafenoSARS-COV-2Biosensorscovid-19detectiongrapheneSARS-COV-2Due to the health emergency produced by SARS-CoV-2, which has generated a pandemic, this work proposes a review on developed methods for the detection of Covid-19 based on graphene biosensors, considering their physicochemical properties. This research includes a compilation and analysis of information on this type of biosensors published in high-impact journals in recent years. For the development of the study, parameters such as detection time, detection limit, type of sensor, proteins that the biosensor detects, type of graphene, and cost were chosen to verify its effectiveness. The analyzed results demonstrate that most biosensors functionalizing the antibody of S, N protein or recombination of both, and some biosensors allow the detection of up to 4 types of proteins (C-reactive protein, IgG, IgM, and nucleapside). Several of the analyzed studies show a specific sequence detection of the virus and a low limit of detection (LOD) ranging from 0.1 fg/mL to 1 fg/mL, which allows detecting SARS-CoV-2 at low concentrations. In conclusion, the analysis indicates a feasible option for the implementation of graphene-based biosensors as an alternative to traditional test.Debido a la emergencia sanitaria producida por el SARS-CoV-2 que ha generado una pandemia, en este trabajo se propone una revisión sobre métodos desarrollados para la detección de Covid-19 basados en biosensores de grafeno, considerando sus propiedades fisicoquímicas. Esta investigación abarca una recopilación y análisis de información sobre biosensores en revistas de alto impacto en los últimos dos años. Para el desarrollo del estudio, se escogieron parámetros como: tiempo de detección, límite de detección, tipo de sensor, proteínas que detecta el biosensor, tipo de grafeno y costo, a fin de comprobar su efectividad. Los resultados analizados demuestran que la mayoría de biosensores funcionalizan el anticuerpo de la proteína S, N o una recombinación de ambas, y, algunos biosensores permiten la detección de hasta 4 tipos de proteínas (proteína reactiva C, IgG, IgM y nucleapside). Varios de los estudios analizados muestran una detección de secuencia especifica del virus y un bajo límite de detección (LOD) que va desde 0,1 fg/mL hasta a 1 fg/mL, lo que permite detectar SARS-CoV-2 a bajas concentraciones. El análisis indica una opción factible para la implementación de biosensores basados en grafeno como alternativa a las pruebas tradicionales.Facultad de Ingeniería en Geología, Minas, Petróleos y Ambiental - Universidad Central del Ecuador2021-12-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/xmlapplication/ziphttps://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/351910.29166/revfig.v12i2.3519FIGEMPA: Investigación y Desarrollo; Vol. 12 No. 2 (2021): Rediscover; 70-84FIGEMPA: Investigación y Desarrollo; Vol. 12 Núm. 2 (2021): Reencuentro; 70-842602-84841390-704210.29166/revfig.v12i2reponame:Revista FIGEMPA: Investigación y Desarrolloinstname:Universidad Central del Ecuadorinstacron:UCEspahttps://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4305https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4348https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519/4349Derechos de autor 2021 Daniel Mena-Lizano, Eliana Acurio, Richard Pachacama-Choca, Gabriela Tubón-Uscahttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccess2022-01-27T19:50:30Zoai:revistadigital.uce.edu.ec:article/3519Portal de revistashttps://revistadigital.uce.edu.ec/Universidad públicahttps://uce.edu.ec/**Ecuador*602-84841390-7042opendoar:02022-01-27T19:50:30Revista FIGEMPA: Investigación y Desarrollo - Universidad Central del Ecuadorfalse |
| spellingShingle | Review about graphene- based biosensors for detection of SARS-COV-2 Mena-Lizano, Daniel Biosensores covid-19 detección grafeno SARS-COV-2 Biosensors covid-19 detection graphene SARS-COV-2 |
| status_str | publishedVersion |
| title | Review about graphene- based biosensors for detection of SARS-COV-2 |
| title_full | Review about graphene- based biosensors for detection of SARS-COV-2 |
| title_fullStr | Review about graphene- based biosensors for detection of SARS-COV-2 |
| title_full_unstemmed | Review about graphene- based biosensors for detection of SARS-COV-2 |
| title_short | Review about graphene- based biosensors for detection of SARS-COV-2 |
| title_sort | Review about graphene- based biosensors for detection of SARS-COV-2 |
| topic | Biosensores covid-19 detección grafeno SARS-COV-2 Biosensors covid-19 detection graphene SARS-COV-2 |
| url | https://revistadigital.uce.edu.ec/index.php/RevFIG/article/view/3519 |