Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis.
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2024
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| 在線閱讀: | https://www.dspace.uce.edu.ec/handle/25000/33207 |
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| author | Echeverría, Gustavo |
| author2 | Zumárraga, Martín J. Proaño Pérez, Freddy Barceló Blasco, Francisco H. de Waard, Jacobus |
| author2_role | author author author author |
| author_facet | Echeverría, Gustavo Zumárraga, Martín J. Proaño Pérez, Freddy Barceló Blasco, Francisco H. de Waard, Jacobus |
| author_role | author |
| collection | Repositorio de la Universidad Central del Ecuador |
| dc.creator.none.fl_str_mv | Echeverría, Gustavo Zumárraga, Martín J. Proaño Pérez, Freddy Barceló Blasco, Francisco H. de Waard, Jacobus |
| dc.date.none.fl_str_mv | 2024-03-19T20:25:01Z 2024-03-19T20:25:01Z 2024-03-02 |
| dc.format.none.fl_str_mv | 9 páginas application/pdf application/pdf |
| dc.identifier.none.fl_str_mv | Echeverría, G., Zumárraga, M.J., Proaño-Pérez, F. et al. Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. Sci Rep 14, 5155 (2024). https://doi.org/10.1038/s41598-024-52089-1 https://www.dspace.uce.edu.ec/handle/25000/33207 2045-2322 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Nature Publishing Group United Kingdom |
| dc.relation.none.fl_str_mv | 9 1 Volmen 14, Tomo 5155 Scientific Reports |
| dc.rights.none.fl_str_mv | Atribución 4.0 Internacional (CC BY 4.0) info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | https://doi.org/10.1038/s41598-024-52089-1 reponame:Repositorio de la Universidad Central del Ecuador instname:Universidad Central del Ecuador instacron:UCE |
| dc.subject.none.fl_str_mv | tuberculin PPD bovine tuberculosis |
| dc.title.none.fl_str_mv | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| dc.type.none.fl_str_mv | Artículo de revista http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/coar/version/c_970fb48d4fbd8a85 Text info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | tablas, gráficos |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UCE_ba1ba48c10ef219ede12828ddf8ce4e7 |
| identifier_str_mv | Echeverría, G., Zumárraga, M.J., Proaño-Pérez, F. et al. Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. Sci Rep 14, 5155 (2024). https://doi.org/10.1038/s41598-024-52089-1 2045-2322 |
| instacron_str | UCE |
| institution | UCE |
| instname_str | Universidad Central del Ecuador |
| language | eng |
| network_acronym_str | UCE |
| network_name_str | Repositorio de la Universidad Central del Ecuador |
| oai_identifier_str | oai:dspace.uce.edu.ec:25000/33207 |
| publishDate | 2024 |
| publisher.none.fl_str_mv | Nature Publishing Group United Kingdom |
| reponame_str | Repositorio de la Universidad Central del Ecuador |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio de la Universidad Central del Ecuador - Universidad Central del Ecuador |
| repository_id_str | 2487 |
| rights_invalid_str_mv | Atribución 4.0 Internacional (CC BY 4.0) |
| spelling | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis.Echeverría, GustavoZumárraga, Martín J.Proaño Pérez, FreddyBarceló Blasco, FranciscoH. de Waard, Jacobustuberculin PPDbovine tuberculosistablas, gráficosAlthough several brands of tuberculin purified protein derivatives (PPDs) are available for diagnosing bovine tuberculosis (bTB), comparative studies to determine their diagnostic accuracy are infrequent. In Ecuador we compared two different PPD brands for bTB diagnosis using skin testing and measuring skin thickness increase. Additionally, we evaluated four PPD brands, including those used for skin testing, in the Bovine Tuberculosis Interferon Gamma Test (IFN-γ test) measuring IFN-γ induction in whole blood. The study included 17 naturally tuberculosis-infected PPD and IFN-γ test positive bovines. Both the field and laboratory results showed significant differences in classifying the 17 bovines as bTB positive or negative. We hypothesize that several factors, such as the genetic background of the cows, sensitization to environmental mycobacteria, M. bovis strains involved in the bTB infection, and the manufacturing procedures of the PPDs, could have influenced the immune reaction toward the different tuberculin PPD brands. Our study emphasizes the necessity for comparative studies aimed at determining the diagnostic accuracy of PPD brands for bTB diagnosis as well as the development of standardized methods for PPD production and potency determination.Nature Publishing GroupUnited Kingdom2024-03-19T20:25:01Z2024-03-19T20:25:01Z2024-03-02Artículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9 páginasapplication/pdfapplication/pdfEcheverría, G., Zumárraga, M.J., Proaño-Pérez, F. et al. Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. Sci Rep 14, 5155 (2024). https://doi.org/10.1038/s41598-024-52089-1https://www.dspace.uce.edu.ec/handle/25000/332072045-2322https://doi.org/10.1038/s41598-024-52089-1reponame:Repositorio de la Universidad Central del Ecuadorinstname:Universidad Central del Ecuadorinstacron:UCEeng91Volmen 14, Tomo 5155Scientific ReportsAl consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores.Atribución 4.0 Internacional (CC BY 4.0)info:eu-repo/semantics/openAccess2024-12-11T09:45:30Zoai:dspace.uce.edu.ec:25000/33207Institucionalhttp://www.dspace.uce.edu.ec/Universidad públicahttps://www.uce.edu.ec/http://www.dspace.uce.edu.ec/oai.Ecuador...opendoar:24872024-12-11T09:45:30Repositorio de la Universidad Central del Ecuador - Universidad Central del Ecuadorfalse |
| spellingShingle | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. Echeverría, Gustavo tuberculin PPD bovine tuberculosis |
| status_str | publishedVersion |
| title | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| title_full | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| title_fullStr | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| title_full_unstemmed | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| title_short | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| title_sort | Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis. |
| topic | tuberculin PPD bovine tuberculosis |
| url | https://www.dspace.uce.edu.ec/handle/25000/33207 |