Ibuprofeno en el tratamiento del ductus arterioso permeable (Revisión bibliográfica)

ABSTRACT The persistence of patent ductus arteriosus is a frequent malformation in newborns; in the great majority of them there is a physiological closure during the first days of birth; in other cases, the communication persists being denominated persistence of patent ductus arteriosus. Current therapeutic schemes include medication or surgical procedures; ibuprofen is one of the drugs that have been used for this disease; however, there is no consensus and clarity on its therapeutic effects as a coadjuvant for the closure of ductus arteriosus. The aim of this research was to update the knowledge related to the advantages of ibuprofen as a therapeutic agent in patients with patent ductus arteriosus. For this purpose, a basic, descriptive, cross-sectional investigation was carried out consisting of a bibliographic review of documents published in the last five years. A total of 51 documents were identified, of which thirty-three were used in the study. The information was obtained from regional databases (Latindex, Lilacs, Scielo and Redalyc) and high impact databases (Scopus, Medline, PubMed and Ice Web of Sciencie). The main results include the description of the anatomopathological characteristics, causes or conditions that generate duct patency, as well as the pharmacokinetic characteristics of ibuprofen and the advantages of its use in ductus arteriosus closure. It is concluded that there is scientific evidence that supports the use of ibuprofen as a drug with proven effectiveness in the closure of patent ductus arteriosus. Keywords: Cyanosis; Ductus arteriosus; Ibuprofen; Cardiovascular malformation. Reviewed by: Lic. Doris Chuquimarca, Mgs. ESL PROFESSOR C.I. 060449038-3

• Päätekijä: Urbano Solis Cartas (author)
• Aineistotyyppi: bachelorThesis
• Kieli: spa
• Julkaistu: 2023
• Aiheet: Cianosis; Conducto arterioso; Ibuprofeno; Malformación cardiovascular
• Linkit: http://dspace.unach.edu.ec/handle/51000/10341