Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores
Anemia in older adults is a common and multifactorial health problem, with an estimated 10% to 30% of this group presenting with anemia, and its frequency increases with age and the presence of chronic diseases. The objective of this literature review was to gather information on vitamin B12 and fer...
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| Médium: | bachelorThesis |
| Jazyk: | spa |
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2025
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| On-line přístup: | http://dspace.unach.edu.ec/handle/51000/15759 |
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| _version_ | 1862821887975882752 |
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| author | Punina Chimborazo, Jhonny Gustavo |
| author_facet | Punina Chimborazo, Jhonny Gustavo |
| author_role | author |
| collection | Repositorio Universidad Nacional de Chimborazo |
| dc.contributor.none.fl_str_mv | Martínez Durán, Eliana Elizabeth |
| dc.creator.none.fl_str_mv | Punina Chimborazo, Jhonny Gustavo |
| dc.date.none.fl_str_mv | 2025-07-29T21:41:41Z 2025-07-29T21:41:52Z 2025-07-29T21:41:41Z 2025-07-29T21:41:52Z 2025-07-29 |
| dc.format.none.fl_str_mv | 61 páginas |
| dc.identifier.none.fl_str_mv | Punina Ch., Jhonny G. (2025) Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores. (Tesis de Grado) Universidad Nacional de Chimborazo). Riobamba, Ecuador. UNACH-EC-FCS-LCL http://dspace.unach.edu.ec/handle/51000/15759 |
| dc.language.none.fl_str_mv | spa |
| dc.publisher.none.fl_str_mv | Riobamba: Universidad Nacional de Chimborazo |
| dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio Universidad Nacional de Chimborazo instname:Universidad Nacional de Chimborazo instacron:UNACH |
| dc.subject.none.fl_str_mv | Vitamina B12 Ferritina Hierro sérico Ácido fólico Hemoglobina |
| dc.title.none.fl_str_mv | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/bachelorThesis |
| description | Anemia in older adults is a common and multifactorial health problem, with an estimated 10% to 30% of this group presenting with anemia, and its frequency increases with age and the presence of chronic diseases. The objective of this literature review was to gather information on vitamin B12 and ferritin levels for the diagnosis of anemia in elderly patients, including laboratory methods and clinical manifestations. It is a documentary, non-experimental research of a retrospective and cross-sectional type. 46 scientific articles were reviewed, of which 30 were selected through inclusion and exclusion criteria. The information was obtained from scientific databases, including Google Scholar, Redalyc, PubMed, ScienceDirect, Journal of Cell Biology, Journal of Contemporary Medicine, WHO, Oceanomedicine, Scielo, ASEI, Geosalud, Ocronos, PAHO, and BVS. Through the analysis and discussion of various authors, the proposed objectives were achieved, demonstrating the effectiveness of immunoassays, particularly chemiluminescence and holotranscobalamin, which surpass the utility of serum B12. The most frequently found clinical manifestations were peripheral neuropathy, cognitive impairment, in addition to classic symptoms such as fatigue and pallor. These can be atypical and subtle on many occasions; therefore, the clinical evaluation must be thorough, considering both the symptoms and the patient's comorbidities, and complemented with precise laboratory tests for an adequate diagnosis and management. |
| eu_rights_str_mv | openAccess |
| format | bachelorThesis |
| id | UNACH_37cb845eaab0ec8a9d295e9a29456fde |
| identifier_str_mv | Punina Ch., Jhonny G. (2025) Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores. (Tesis de Grado) Universidad Nacional de Chimborazo). Riobamba, Ecuador. UNACH-EC-FCS-LCL |
| instacron_str | UNACH |
| institution | UNACH |
| instname_str | Universidad Nacional de Chimborazo |
| language | spa |
| network_acronym_str | UNACH |
| network_name_str | Repositorio Universidad Nacional de Chimborazo |
| oai_identifier_str | oai:localhost:51000/15759 |
| publishDate | 2025 |
| publisher.none.fl_str_mv | Riobamba: Universidad Nacional de Chimborazo |
| reponame_str | Repositorio Universidad Nacional de Chimborazo |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio Universidad Nacional de Chimborazo - Universidad Nacional de Chimborazo |
| repository_id_str | 0 |
| rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ |
| spelling | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayoresPunina Chimborazo, Jhonny GustavoVitamina B12FerritinaHierro séricoÁcido fólicoHemoglobinaAnemia in older adults is a common and multifactorial health problem, with an estimated 10% to 30% of this group presenting with anemia, and its frequency increases with age and the presence of chronic diseases. The objective of this literature review was to gather information on vitamin B12 and ferritin levels for the diagnosis of anemia in elderly patients, including laboratory methods and clinical manifestations. It is a documentary, non-experimental research of a retrospective and cross-sectional type. 46 scientific articles were reviewed, of which 30 were selected through inclusion and exclusion criteria. The information was obtained from scientific databases, including Google Scholar, Redalyc, PubMed, ScienceDirect, Journal of Cell Biology, Journal of Contemporary Medicine, WHO, Oceanomedicine, Scielo, ASEI, Geosalud, Ocronos, PAHO, and BVS. Through the analysis and discussion of various authors, the proposed objectives were achieved, demonstrating the effectiveness of immunoassays, particularly chemiluminescence and holotranscobalamin, which surpass the utility of serum B12. The most frequently found clinical manifestations were peripheral neuropathy, cognitive impairment, in addition to classic symptoms such as fatigue and pallor. These can be atypical and subtle on many occasions; therefore, the clinical evaluation must be thorough, considering both the symptoms and the patient's comorbidities, and complemented with precise laboratory tests for an adequate diagnosis and management.La anemia en adultos mayores es un problema de salud común y multifactorial, estimándose que entre el 10% y el 30% de este grupo presentan anemia y su frecuencia aumenta con la presencia de edad y enfermedades crónicas. El objetivo de esta revisión bibliográfica fue recopilar información sobre los niveles de vitamina B12 y ferritina para el diagnóstico de anemia en pacientes adultos mayores como los métodos de laboratorio y manifestaciones clínicas. Es una investigación documental, no experimental, de tipo retrospectivo y corte transversal. Se revisaron 46 artículos científicos, de estos 30 fueron seleccionados por medio de los criterios de inclusión y exclusión. La información obtenida fue de bases de datos científicos como Google académico, Redalyc, Pubmed, Science Direct, Journal of Cell Biology, Journal of Contemporary Medicine, OMS, Oceanomedicina, Scielo, ASEI, Geosalud, Ocronos, OPS, BVS. Con el análisis y discusión de diferentes autores se logró cumplir con los objetivos propuestos, evidenciándose el uso de la inmunoanálisis, especialmente la quimioluminiscencia y la holotranscobalamina como métodos eficaces, los cuales superan la utilidad de la B12 sérica. Las manifestaciones clínicas encontradas con mayor frecuencia fueron la neuropatía periférica, deterioro cognitivo, además de los síntomas clásicos como fatiga y palidez. Estas pueden ser atípicas y sutiles en muchas ocasiones, por lo cual, la evaluación clínica debe ser exhaustiva, considerando tanto los síntomas como las comorbilidades del paciente y complementada con pruebas de laboratorio precisas para un diagnóstico y manejo adecuados.UNACH, EcuadorRiobamba: Universidad Nacional de ChimborazoMartínez Durán, Eliana Elizabeth2025-07-29T21:41:41Z2025-07-29T21:41:52Z2025-07-29T21:41:41Z2025-07-29T21:41:52Z2025-07-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesis61 páginasPunina Ch., Jhonny G. (2025) Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores. (Tesis de Grado) Universidad Nacional de Chimborazo). Riobamba, Ecuador.UNACH-EC-FCS-LCLhttp://dspace.unach.edu.ec/handle/51000/15759spahttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Nacional de Chimborazoinstname:Universidad Nacional de Chimborazoinstacron:UNACH2025-11-14T08:29:25Zoai:localhost:51000/15759Institucionalhttp://dspace.unach.edu.ec/Universidad públicahttps://www.unach.edu.ec/http://dspace.unach.edu.ec/oai.Ecuador...opendoar:02025-11-14T08:29:25Repositorio Universidad Nacional de Chimborazo - Universidad Nacional de Chimborazofalse |
| spellingShingle | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores Punina Chimborazo, Jhonny Gustavo Vitamina B12 Ferritina Hierro sérico Ácido fólico Hemoglobina |
| status_str | publishedVersion |
| title | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| title_full | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| title_fullStr | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| title_full_unstemmed | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| title_short | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| title_sort | Vitamina B12 y ferritina para el diagnóstico de anemia pacientes adultos mayores |
| topic | Vitamina B12 Ferritina Hierro sérico Ácido fólico Hemoglobina |
| url | http://dspace.unach.edu.ec/handle/51000/15759 |