Marcador tumoral CA-125 como apoyo al diagnóstico de Cáncer de Ovario.
Ovarian cancer represents one of the main health problems in women due to its high mortality rate and generally late diagnosis. In its early stages, it often goes unnoticed, as the symptoms are mild or nonspecific. This has driven the search for tools that allow for earlier detection and appropriate...
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| Formaat: | bachelorThesis |
| Taal: | spa |
| Gepubliceerd in: |
2026
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| Onderwerpen: | |
| Online toegang: | http://dspace.unach.edu.ec/handle/51000/16512 |
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Voeg label toe | Samenvatting: | Ovarian cancer represents one of the main health problems in women due to its high mortality rate and generally late diagnosis. In its early stages, it often goes unnoticed, as the symptoms are mild or nonspecific. This has driven the search for tools that allow for earlier detection and appropriate follow-up. In this context, the tumor marker CA-125 has become an important support for both diagnosis and treatment evaluation. This study sought to evaluate the usefulness of the tumor marker CA-125 in the diagnosis of ovarian cancer, focusing on its sensitivity, specificity, correlation with therapeutic response, and relationship with the clinical stage. The research employed a qualitative, descriptive, documentary, and cross-sectional approach. Forty scientific articles from databases such as Scopus, Web of Science, and SciELO were examined. After applying the inclusion and exclusion criteria, 22 updated studies were selected, providing important evidence on the marker's efficacy across different clinical settings. The results demonstrated that CA-125 exhibits high sensitivity in advanced stages, exceeding 80%; however, its effectiveness decreases in early stages. Analysis showed that a gradual decrease in its levels after surgery or chemotherapy is associated with a better prognosis, while an increase indicates relapse. In conclusion, the tumor marker CA-125 is an advantageous tool in the management of ovarian cancer, although its use should be combined with imaging studies and other biomarkers to improve diagnosis and clinical follow-up. |
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