Cuantificación de vitamina D en el diagnóstico de enfermedades autoinmunes

ABSTRACT Vitamin D contributes significantly to the control of infections and autoimmune diseases; thanks to its action on the vitamin D receptor, it is located in most immune cells and acts on the immune system in innate and adaptive immunity. These immune cells play an essential role in the individual because of their multiple specific functions such as inhibition of self-reactive cells, reducing pro-inflammatory cytokines' production enhances apoptosis. This research aimed to collect bibliographic information on the quantification of vitamin D in the diagnosis of autoimmune diseases. This study is descriptive, documentary with a transverse cohort. Fifty-four bibliographies were analyzed about the immunological function of vitamin D, methods of analysis, and the concentrations in different autoimmune diseases published in the lapse of 10 years ago. That is to say, from 2011 to the present date, collected this information from books, scientific articles of high impact, such as Books, PubMed, Scielo, Medigraphic, Elsevier, Google Scholar, Nutrients, Redalyc. According to the lectures analyzed, most patients with autoimmune diseases had serum vitamin D concentrations lower than the reference values, 56 % insufficiency, and 28.6 % deficiency; this demonstrates the need for highly sensitive dosages to control the different autoimmune disorders. KEY WORDS: vitamin d, autoimmune disease, immunity. Reviewed by: Ms.C. Ana Maldonado León ENGLISH PROFESSOR C.I.0601975980

• Hovedforfatter: Lisseth Maribel, Rumancela Guamán (author)
• Format: bachelorThesis
• Sprog: spa
• Udgivet: 2021
• Fag: vitamina D; enfermedad autoinmune; inmunidad
• Online adgang: http://dspace.unach.edu.ec/handle/51000/7981