El sobrepeso y la obesidad como factores que influyen en la transferencia placentaria de ácidos grasos en gestantes con diabetes gestacional.

Gestational diabetes mellitus (GDM) and obesity represent significant metabolic conditions during pregnancy, associated with metabolic, inflammatory, and vascular alterations that impact both the mother and the fetus. These conditions affect maternal metabolic and vascular homeostasis, contributing...

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Bibliographische Detailangaben
1. Verfasser: Quenguan Ruano, Joselin Alejandra (author)
Format: bachelorThesis
Sprache:spa
Veröffentlicht: 2025
Schlagworte:
Online Zugang:http://dspace.unach.edu.ec/handle/51000/15085
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Zusammenfassung:Gestational diabetes mellitus (GDM) and obesity represent significant metabolic conditions during pregnancy, associated with metabolic, inflammatory, and vascular alterations that impact both the mother and the fetus. These conditions affect maternal metabolic and vascular homeostasis, contributing to severe obstetric and neonatal complications. Understanding the underlying mechanisms and implementing preventive strategies are essential to addressing these health challenges. Research from the last five years focusing on these topics in the context of women with GDM was included, applying rigorous inclusion criteria. The incidence of obesity and overweight in women with GDM is high, with alterations observed in glycemic control, lipid profiles, hemograms, and coagulation parameters. Elevated levels of inflammatory adipokines and biomarkers of inflammation were identified in women with obesity compared to those without. The proposed prevention strategies include intervention plans that combine metabolic monitoring, personalized dietary programs, adapted physical activity, and educational workshops. Conclusions. Obesity and GDM have a significant impact on maternal and fetal health, evidenced by metabolic and vascular alterations.