Eficacia antifúngica e inhibitoria in vitro de Nistatina versus aceite esencial de Melaleuca alternifolia sobre Candida albicans
ABSTRACT: The use of essential oils in dentistry has increased in recent years due to their antimicrobial, anti-inflammatory, and antifungal properties. In this study, the antifungal activity of tea tree essential oil (Melaleuca alternifolia) versus Candida albicans and subsequently their results we...
Wedi'i Gadw mewn:
| Prif Awdur: | |
|---|---|
| Fformat: | bachelorThesis |
| Iaith: | spa |
| Cyhoeddwyd: |
2022
|
| Pynciau: | |
| Mynediad Ar-lein: | http://dspace.unach.edu.ec/handle/51000/9666 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|
Ychwanegu Tag | Crynodeb: | ABSTRACT: The use of essential oils in dentistry has increased in recent years due to their antimicrobial, anti-inflammatory, and antifungal properties. In this study, the antifungal activity of tea tree essential oil (Melaleuca alternifolia) versus Candida albicans and subsequently their results were compared with those of Nystatin, a first-line drug to treat fungal infections; The study was observational, descriptive, cross-sectional and in vitro. The present investigation was carried out with 30 Petri dishes inoculated with the fungus Candida albicans in Sabouraud Agar and subsequently sterile disks embedded with essential oil of tea tree (Melaleuca alternifolia) in concentrations of 50%, 75%, and 100%. The positive control was made with Nystatin (C+), while the negative control was with distilled water (C-). The Petri dishes were incubated at 37.5°C for 48 hours. The results obtained were processed and analyzed in the SPSS 25 program. It was concluded that the essential oil of tea tree (Melaleuca alternifolia) in its 100% concentration was the most effective against strains of Candida albicans with values of 13.4 mm. Nystatin obtained an inhibitory halo of 33.4 mm. In comparison, the least effective extract was tea tree essential oil at a concentration of 50%, having an inhibition halo of 5.1 mm, similar to the negative control. Finally, there were statistically significant differences between Melaleuca alternifolia and Nystatin (p = 0.000); however, when measuring the results on the Duraffourd scale, it was susceptible, as was Nystatin (C+). Keywords: Essential oils, antifungal activity, Nystatin, tea tree essential oil, Candida albicans, Melaleuca alternifolia. |
|---|