Caracterización clínica y pruebas de laboratorio para el diagnóstico de Talasemia.

Thalassemia is a genetic blood disorder that affects hemoglobin production, causing anemia and other health problems. It is classified depending on the severity, so that it can be mild or severe, requiring different forms of treatment, such as blood transfusions and iron chelation therapy. Patients may experience fatigue, weakness, pallor and other symptoms. The aim of the research project was to analyze clinical features and tests for thalassemia diagnosis through updated literature reviews in order to organize and interpret this health-relevant information. The study was carried out with a qualitative approach at a descriptive level of bibliographic and non-experimental documentary design. With a population of 50 bibliographies where it was chosen through the inclusion and exclusion criteria to obtain the sample of 30 scientific articles selected from scientific databases such as: Redalyc, Scielo, Medigraphic, PubMed and Google Scholar. The most common pathologies were splenomegaly (33.33%) and hemolytic anemia (20%), and the most frequently performed analyses to identify these diseases were Hb (52.38%) and Hb electrophoresis (28.57%). Subsequently, general symptoms of this disease were identified as pallor (53.84%) followed by jaundice (23.07%) and other general symptoms such as fatigue, dizziness, headache, growth retardation. Finally, the most frequently used laboratory test was hemogram and Hb (14.28%) followed by HbF (9.52%). In conclusion, early identification of clinical signs combined with specific tests allows an accurate and timely diagnosis of the disease.

• 1. Verfasser: Sánchez Paguay, Karina Maribel (author)
• Format: bachelorThesis
• Sprache: spa
• Veröffentlicht: 2024
• Schlagworte: Talasemia; Hemoglobina; Biometría Hemática; Pruebas de laboratorio; Anemia
• Online Zugang: http://dspace.unach.edu.ec/handle/51000/12783