Lactato sérico como biomarcador pronóstico en sepsis neonatal Hospital General Riobamba, 2019-2020
ABSTRACT Neonatal sepsis continues to be a challenge because it constitutes one of the main causes of morbidity and mortality despite better obstetric management and the use of antibiotic therapy. Timely identification is a fundamental piece since the suspicion of neonatal sepsis is based on the gro...
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| Formato: | bachelorThesis |
| Idioma: | spa |
| Publicado em: |
2021
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| Acesso em linha: | http://dspace.unach.edu.ec/handle/51000/7992 |
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Adicionar Tag | Resumo: | ABSTRACT Neonatal sepsis continues to be a challenge because it constitutes one of the main causes of morbidity and mortality despite better obstetric management and the use of antibiotic therapy. Timely identification is a fundamental piece since the suspicion of neonatal sepsis is based on the grouping of perinatal risk factors as well as signs and symptoms that are not sensitive or specific for this pathology; In addition, diagnostic tests had poor positive predictive accuracy. Faced with this problem, prognostic biomarkers such as serum lactate have taken on significant importance as a diagnostic support in neonatal sepsis, taking values greater than 2 mmol / l as positive. An observational, retrospective and cross-sectional study presented with a population of 103 cases admitted with a diagnosis of neonatal sepsis at the Riobamba General Hospital during 2019-2020 period, of which 21 cases meet the inclusion criteria, presenting with an average of 4 , 25 mmol / L, a minimum value of 1.75 mmol / L and a maximum of 9.12 mmol / L. Neonatal sepsis is presented in relation to variables: gestational age 42.9% (n = 9) early term neonates; 61.9% (n = 13) adequate weight at birth and the risk factors that occur with the highest incidence 28.6% (n = 6) Maternal genitourinary infection in childbirth; 14.3% (n = 3) Colonization of microorganisms from the maternal genital tract; 14.3% (n = 3) Premature rupture of membranes; 9.5% (n = 2) Mother COVID IGG + IGM +; 4.8% (n = 1) Home delivery; 28.6% (n = 6) Other causes. Key words: neonatal sepsis, prognostic biomarkers, serum lactate, risk factors. Reviewed by: Mgs. Maritza Chávez Aguagallo ENGLISH PROFESSOR c.c. 0602232324 |
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