Queratoquiste odontogénico, diagnóstico y opciones terapéuticas.
The odontogenic keratocyst is a pathologic entity of great interest in the field of dentistry and oral pathology due to its distinctive histologic characteristics, its clinical behavior and its association with Gorlin-Goltz syndrome. This literature review aims to analyze the histologic variables, t...
Kaydedildi:
| Yazar: | |
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| Materyal Türü: | bachelorThesis |
| Dil: | spa |
| Baskı/Yayın Bilgisi: |
2024
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| Konular: | |
| Online Erişim: | http://dspace.unach.edu.ec/handle/51000/13991 |
| Etiketler: |
Etiketle
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Etiketle | Özet: | The odontogenic keratocyst is a pathologic entity of great interest in the field of dentistry and oral pathology due to its distinctive histologic characteristics, its clinical behavior and its association with Gorlin-Goltz syndrome. This literature review aims to analyze the histologic variables, therapeutic options, recurrence rates and the relationship between odontogenic keratocyst and Gorlin-Goltz syndrome. An exhaustive search was carried out in PubMed, Scopus, Web of Science and SciELO databases using predefined keywords and search equations. Inclusion and exclusion criteria were applied to select the most relevant articles published in the last 10 years (2014-2024). A total of 40 articles were selected for analysis. The results revealed that odontogenic keratocyst presents histological features: as a parakeratinized stratified squamous epithelium. In addition, aspects such as high recurrence rate, aggressive behavior and the presence of satellite cysts were highlighted. In terms of therapeutic options, surgical approaches such as enucleation, resection and marsupialization/decompression were identified, along with adjuvant therapies such as Carnoy's solution, cryotherapy, peripheral ostectomy and 5- fluorouracil. Recurrence rates varied according to treatment modality, with resection having the lowest rates and marsupialization the highest. A close relationship was found between odontogenic keratocyst and Gorlin-Goltz syndrome, with keratocysts being a distinctive and common feature of this genetic disorder. Patients with Gorlin-Goltz syndrome showed an increased likelihood of developing multiple keratocysts, which tended to be more aggressive and recurrent compared to sporadic cases. In conclusion, odontogenic keratocyst is a complex entity that requires a multidisciplinary approach to its diagnosis and treatment. Understanding the histologic variables, therapeutic options, recurrence rates and the relationship with Gorlin-Goltz syndrome is fundamental for the proper management of this lesion. Collaboration between oral health professionals, pathologists, and other specialists is recommended, as well as continued research to improve strategies for diagnosis, treatment, and follow-up of patients with odontogenic keratocyst. |
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