Pruebas de laboratorio en la valoración de la hemostasia primaria
Hemostasis is a physiological process that occurs in two phases, primary and secondary. In the first one, the platelet plug is formed, which begins seconds after the vessel injury; the objective of the research was to specify the different laboratory tests in the assessment of primary hemostasis, as...
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| Andere auteurs: | |
| Formaat: | bachelorThesis |
| Taal: | spa |
| Gepubliceerd in: |
2024
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| Onderwerpen: | |
| Online toegang: | http://dspace.unach.edu.ec/handle/51000/12836 |
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Voeg label toe | Samenvatting: | Hemostasis is a physiological process that occurs in two phases, primary and secondary. In the first one, the platelet plug is formed, which begins seconds after the vessel injury; the objective of the research was to specify the different laboratory tests in the assessment of primary hemostasis, as well as the causes that produce the quantitative and functional alterations of the platelets. The present work had a qualitative, descriptive approach, with a documentary, non-experimental, cross-sectional cohort, and retrospective design. The information was extracted from different scientific databases such as: Elsevier, Google academic, Medigraphic, Scielo, Science Direct and PubMed, with a population of 65 scientific articles, in which inclusion and exclusion criteria were applied, obtaining a sample of 30. The research showed that the different tests used in the diagnosis of primary hemostasis disorders are based on conventional manual and automated methods and techniques, such as platelet count, platelet morphology, bleeding time, clot retraction, capillary resistance or fragility test, and ristocetin cofactor activity, and more advanced techniques, such as platelet function analyzer or PFA and platelet aggregation. It was also demonstrated that the causes of thrombocytopenias and thrombocytopathies are of hereditary origin, such as Bernard-Soulier syndrome, or acquired during their lifetime, such as immune thrombocytopenic purpura. In conclusion, the mentioned tests evaluate the functionality of platelets, Von Willebrand factor and the vascular wall, being these fundamental for the evaluation of coagulopathies. |
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