Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp
The increase of bacterial resistance to different antimicrobial drugs is a fact that has shocked the scientific community in recent years, so the use of certain medicinal plants popularly known for their usefulness in the treatment of some infections is a potential therapeutic alternative and a poss...
-д хадгалсан:
| Үндсэн зохиолч: | |
|---|---|
| Формат: | bachelorThesis |
| Хэл сонгох: | spa |
| Хэвлэсэн: |
2025
|
| Нөхцлүүд: | |
| Онлайн хандалт: | https://dspace.uniandes.edu.ec/handle/123456789/19182 |
| Шошгууд: |
Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
|
Шошго нэмэх | _version_ | 1859006562453946368 |
|---|---|
| author | Goyes Baca, María José |
| author_facet | Goyes Baca, María José |
| author_role | author |
| collection | Repositorio Universidad Regional Autónoma de los Andes |
| dc.contributor.none.fl_str_mv | Bermúdez Del Sol, Abdel |
| dc.creator.none.fl_str_mv | Goyes Baca, María José |
| dc.date.none.fl_str_mv | 2025-04-16T21:57:35Z 2025-04-16T21:57:35Z 2025-04 |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | UA-MER-EAC-004-2025 https://dspace.uniandes.edu.ec/handle/123456789/19182 |
| dc.language.none.fl_str_mv | spa |
| dc.rights.none.fl_str_mv | Atribución-NoComercial-SinDerivadas 3.0 Ecuador http://creativecommons.org/licenses/by-nc-nd/3.0/ec/ info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio Universidad Regional Autónoma de los Andes instname:Universidad Regional Autónoma de los Andes instacron:UNIANDES |
| dc.subject.none.fl_str_mv | PLANTAS MEDICINALES EXTRACTOS VEGETALES ORIGANUM MAJORANA PROTEUS SPP ACTIVIDAD ANTIMICROBIANA |
| dc.title.none.fl_str_mv | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/bachelorThesis |
| description | The increase of bacterial resistance to different antimicrobial drugs is a fact that has shocked the scientific community in recent years, so the use of certain medicinal plants popularly known for their usefulness in the treatment of some infections is a potential therapeutic alternative and a possible solution to this problem, that is why this research aimed to evaluate the antimicrobial activity “in vitro” of the hydroethanolic extract of Origanum majorana leaves against Proteus spp; For which it was developed in three stages, a first one to obtain the extract by the maceration method with hydroalcoholic solution with subsequent simple distillation without reflux to eliminate the alcohol and evaluation of the quality of the extract through organoleptic and physicochemical parameters, a second one for its phytochemical characterization by qualitative identification methods and a third stage for the antimicrobial evaluation “in vitro” by the method of disc diffusion. The results obtained were an extract of Origanum majorana L with the required quality and a composition of active metabolites that justify a potential antimicrobial activity: phenolic compounds and/or tannins, flavonoids, triterpenes and/or steroids and saponins. The extracts at different concentrations showed antimicrobial activity against Proteus spp.; the inhibition percentages were significantly higher in the extracts at 75% and 100%, the latter being comparable to the antimicrobial activity of ciprofloxacin. |
| eu_rights_str_mv | openAccess |
| format | bachelorThesis |
| id | UNIANDES_dd8e75e4067e33d9bd3572a458f87edd |
| identifier_str_mv | UA-MER-EAC-004-2025 |
| instacron_str | UNIANDES |
| institution | UNIANDES |
| instname_str | Universidad Regional Autónoma de los Andes |
| language | spa |
| network_acronym_str | UNIANDES |
| network_name_str | Repositorio Universidad Regional Autónoma de los Andes |
| oai_identifier_str | oai:dspace.uniandes.edu.ec:123456789/19182 |
| publishDate | 2025 |
| reponame_str | Repositorio Universidad Regional Autónoma de los Andes |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio Universidad Regional Autónoma de los Andes - Universidad Regional Autónoma de los Andes |
| repository_id_str | 455 |
| rights_invalid_str_mv | Atribución-NoComercial-SinDerivadas 3.0 Ecuador http://creativecommons.org/licenses/by-nc-nd/3.0/ec/ |
| spelling | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus sppGoyes Baca, María JoséPLANTAS MEDICINALESEXTRACTOS VEGETALESORIGANUM MAJORANAPROTEUS SPPACTIVIDAD ANTIMICROBIANAThe increase of bacterial resistance to different antimicrobial drugs is a fact that has shocked the scientific community in recent years, so the use of certain medicinal plants popularly known for their usefulness in the treatment of some infections is a potential therapeutic alternative and a possible solution to this problem, that is why this research aimed to evaluate the antimicrobial activity “in vitro” of the hydroethanolic extract of Origanum majorana leaves against Proteus spp; For which it was developed in three stages, a first one to obtain the extract by the maceration method with hydroalcoholic solution with subsequent simple distillation without reflux to eliminate the alcohol and evaluation of the quality of the extract through organoleptic and physicochemical parameters, a second one for its phytochemical characterization by qualitative identification methods and a third stage for the antimicrobial evaluation “in vitro” by the method of disc diffusion. The results obtained were an extract of Origanum majorana L with the required quality and a composition of active metabolites that justify a potential antimicrobial activity: phenolic compounds and/or tannins, flavonoids, triterpenes and/or steroids and saponins. The extracts at different concentrations showed antimicrobial activity against Proteus spp.; the inhibition percentages were significantly higher in the extracts at 75% and 100%, the latter being comparable to the antimicrobial activity of ciprofloxacin.El incremento de la resistencia bacteriana a diferentes fármacos antimicrobianos es un hecho que ha conmocionado a la comunidad científica en los últimos años, por lo que el uso de ciertas plantas medicinales conocidas popularmente por su utilidad en el tratamiento de algunas infecciones constituye una potencial alternativa terapéutica y una posible solución a esta problemática, es por eso que esta investigación tuvo como objetivo evaluar la actividad antimicrobiana “in vitro” del extracto hidroetanólico de las hojas de Origanum majorana frente a Proteus spp; para lo cual se desarrolló en tres etapas, una primera de obtención del extracto por el método de maceración con solución hidroalcohólica con posterior destilación simple sin reflujo para eliminar el alcohol y evaluación de la calidad del extracto a través de parámetros organolépticos y fisicoquímicos, una segunda para su caracterización fitoquímica por métodos de identificación cualitativa y una tercera etapa para la evaluación antimicrobiana “in vitro” por el método de difusión de discos. Como resultados se obtuvo un extracto de Origanum majorana L. con la calidad requerida y una composición de metabolitos activos que justifican una potencial actividad antimicrobiana: compuestos fenólicos y/o taninos, flavonoides, triterpenos y/o esteroides y saponinas. Los extractos a las concentraciones los extractos a las diferentes concentraciones mostraron actividad antimicrobiana frente a Proteus spp.; siendo los porcentajes de inhibición significativamente mayores en los extractos al 75% y al 100%, este último comparable con la actividad antimicrobiana del ciprofloxacino.Bermúdez Del Sol, Abdel2025-04-16T21:57:35Z2025-04-16T21:57:35Z2025-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfUA-MER-EAC-004-2025https://dspace.uniandes.edu.ec/handle/123456789/19182spaAtribución-NoComercial-SinDerivadas 3.0 Ecuadorhttp://creativecommons.org/licenses/by-nc-nd/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Regional Autónoma de los Andesinstname:Universidad Regional Autónoma de los Andesinstacron:UNIANDES2025-04-16T21:57:35Zoai:dspace.uniandes.edu.ec:123456789/19182Institucionalhttps://dspace.uniandes.edu.ec/Institución privadahttps://www.uniandes.edu.ec/https://dspace.uniandes.edu.ec/oai.Ecuador...opendoar:4552025-04-16T21:57:35Repositorio Universidad Regional Autónoma de los Andes - Universidad Regional Autónoma de los Andesfalse |
| spellingShingle | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp Goyes Baca, María José PLANTAS MEDICINALES EXTRACTOS VEGETALES ORIGANUM MAJORANA PROTEUS SPP ACTIVIDAD ANTIMICROBIANA |
| status_str | publishedVersion |
| title | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| title_full | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| title_fullStr | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| title_full_unstemmed | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| title_short | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| title_sort | Actividad antimicrobiana “in vitro” del extracto hidroetanólico de origanum majorana frente a proteus spp |
| topic | PLANTAS MEDICINALES EXTRACTOS VEGETALES ORIGANUM MAJORANA PROTEUS SPP ACTIVIDAD ANTIMICROBIANA |
| url | https://dspace.uniandes.edu.ec/handle/123456789/19182 |