Biomarcadores salivales para la evaluación del riesgo de caries en la primera infancia

Saliva plays an essential role in the forming and maintaining the balance of the oral microbiota through its functions that help promote oral health, and one of the least known is its potential to serve as a tool to identify biomarkers for the early detection of oral diseases. Caries affects 514 million children worldwide and sometimes progress rapidly to destruction, affecting the future quality of life. Therefore, as a means of prevention, it is relevant to study salivary biomarkers for the early diagnosis of caries in early childhood to stop or reverse the carious process in its early stages, avoiding irreversible dental cavitation. The present literature review study aimed to review from the literature the relationship between salivary pH and early childhood caries and to identify the main salivary proteins related as biomarkers for caries detection, based on the retrieval, critical analysis of articles retrieved from different databases such as Pubmed, Scielo, Scopus, Lilacs, Elsevier, Medline Web of Science, Cochrane Library and Google Scholar, in the period from 2015 to 2023, using keywords indexed in DeCs/MeSH. Based on the research, we concluded that there is no direct relationship between salivary pH and early childhood caries, and the main proteins that stand out as salivary biomarkers for caries assessment are Histatin and B-defensin

• 1. Verfasser: Lozano Hueledel, Cecilia Patricia (author)
• Format: bachelorThesis
• Sprache: spa
• Veröffentlicht: 2024
• Schlagworte: ODONTOLOGÍA; BIOMARCADORES SALIVALES; CARIES DENTAL; PREESCOLAR
• Online Zugang: https://dspace.unl.edu.ec/jspui/handle/123456789/29888