Comportamiento de patrones de resistencia de Gram positivos en el laboratorio clínico de Medilab durante los años 2020-2021

Bacterial resistance is the loss of susceptibility of microorganisms to antimicrobial agents due to changes in their genetic material. At present, Gram-positive bacterial species represent a serious problem for public health. Based on the EXPLANATION above, the present RESEARCH HAS focused on descri...

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Príomhchruthaitheoir: Alejandro Villa, Lorena Valeria (author)
Formáid: bachelorThesis
Teanga:spa
Foilsithe / Cruthaithe: 2024
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Rochtain ar líne:https://dspace.unl.edu.ec/jspui/handle/123456789/29361
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Achoimre:Bacterial resistance is the loss of susceptibility of microorganisms to antimicrobial agents due to changes in their genetic material. At present, Gram-positive bacterial species represent a serious problem for public health. Based on the EXPLANATION above, the present RESEARCH HAS focused on describing the resistance patterns in Gram-positive bacteria, from the antibiogram records performed at the Medilab Clinical Laboratory DURING the years 2020 and 2021. The present study had a quantitative, descriptive, retrospective-transversal design approach, consisting of 139 positive cultures and antibiograms of Gram-positive bacteria performed in the different areas of the Medilab Clinic, in order to identify the percentage of resistance to the antibiotics tested, establish the frequency of Gram-positive bacteria in patients’ samples according to the area where they were treated and compare the behavior of the resistance patterns of these bacteria in the years 2020 and 2021. FROM all the antibiotics tested, there was a higher percentage of resistance to oxacillin with 91.1%, followed by erythromycin with 90.5% and clindamycin with 84.2%. The frequency of isolation of these bacteria was in urine samples with 50 cases (35.9%), and the area of origin of the samples was the ambulatory with 81 cases (58.2%). In conclusion, the percentage of resistance of Gram-positive bacteria to the antibiotics tested was oxacillin, erythromycin and clindamycin; isolated more frequently in urine samples, in the ambulatory area, and in comparison between 2020 and 2021 there was greater resistance to clindamycin, trimethoprim-sulfamethoxazole, levofloxacin, streptomycin and linezolid; while in 2021, there was greater resistance to oxacillin, erythromycin, amoxicillin, penicillin, ampicillin sulbactam, gentamicin and ceftriaxone