Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020

Bacterial resistance to antibiotics is one of the biggest public health problems worldwide, which makes it difficult to control infectious diseases caused by bacterial microorganisms since it generates therapeutic failure, lengthens treatments and increases costs in health care. The microorganism St...

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Autor principal: Castillo Vélez, Ana Janela (author)
Format: bachelorThesis
Idioma:spa
Publicat: 2022
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Accés en línia:https://dspace.unl.edu.ec/jspui/handle/123456789/24548
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author Castillo Vélez, Ana Janela
author_facet Castillo Vélez, Ana Janela
author_role author
collection Repositorio Universidad Nacional de Loja
dc.contributor.none.fl_str_mv Delgado, Iliana Alicia
dc.creator.none.fl_str_mv Castillo Vélez, Ana Janela
dc.date.none.fl_str_mv 2022-02-11T20:44:23Z
2022-02-11T20:44:23Z
2022-02
dc.format.none.fl_str_mv 74 p.
application/pdf
dc.identifier.none.fl_str_mv https://dspace.unl.edu.ec/jspui/handle/123456789/24548
dc.language.none.fl_str_mv spa
dc.publisher.none.fl_str_mv Loja
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/3.0/ec/
info:eu-repo/semantics/openAccess
dc.source.none.fl_str_mv reponame:Repositorio Universidad Nacional de Loja
instname:Universidad Nacional de Loja
instacron:UNL
dc.subject.none.fl_str_mv LABORATORIO CLÍNICO
PATRONES DE RESISTENCIA BACTERIANA
STAPHYLOCOCCUS AUREUS
ANTIBIÓTICOS
dc.title.none.fl_str_mv Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/bachelorThesis
description Bacterial resistance to antibiotics is one of the biggest public health problems worldwide, which makes it difficult to control infectious diseases caused by bacterial microorganisms since it generates therapeutic failure, lengthens treatments and increases costs in health care. The microorganism Staphylococcus spp, is one the of the most studied bacterial groups due to its clinical importance and the high rates of resistance it presents to antibiotics. The most important specie is Staphylococcus aureus, which is considered the most pathogenic, followed by coagulase-negative staphylococci that act as opportunistic pathogens. The following study is descriptive and cross-sectional, its objective is to determine bacterial resistance patterns of Staphylococcus spp from the antibiogram records carried out in the Medilab-Medihospital Clinical Laboratory from 2018 to 2020. In addition, 86 positive cultures were isolated for Staphylococcus spp, the studied showed that Staphylococcus aureus and Staphylococcus epidermidis are the most frequent in the outpatient area with 71.43% and 78.40% respectively with predominance in secretion samples with 77.6% and 67.6%. The resistance profile of Staphylococcus aureus against the antibiotics tested in the microbiology laboratory are the following: penicillin (87%), oxacillin (81.50%) and erythromycin (64.6%); while that of Staphylococcus epidermidis was: penicillin (75%), oxacillin (66.7%), erythromycin (62.9%), and clindamycin (52.8%). It is concluded that in both groups of microorganisms they express phenotypes of resistance to oxacillin, penicillin and erythromycin, besides sensitivity to vancomycin and linezolid and variable susceptibility to the rest of the antibiotics evaluated.
eu_rights_str_mv openAccess
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network_name_str Repositorio Universidad Nacional de Loja
oai_identifier_str oai:dspace.unl.edu.ec:123456789/24548
publishDate 2022
publisher.none.fl_str_mv Loja
reponame_str Repositorio Universidad Nacional de Loja
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repository.name.fl_str_mv Repositorio Universidad Nacional de Loja - Universidad Nacional de Loja
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spelling Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020Castillo Vélez, Ana JanelaLABORATORIO CLÍNICOPATRONES DE RESISTENCIA BACTERIANASTAPHYLOCOCCUS AUREUSANTIBIÓTICOSBacterial resistance to antibiotics is one of the biggest public health problems worldwide, which makes it difficult to control infectious diseases caused by bacterial microorganisms since it generates therapeutic failure, lengthens treatments and increases costs in health care. The microorganism Staphylococcus spp, is one the of the most studied bacterial groups due to its clinical importance and the high rates of resistance it presents to antibiotics. The most important specie is Staphylococcus aureus, which is considered the most pathogenic, followed by coagulase-negative staphylococci that act as opportunistic pathogens. The following study is descriptive and cross-sectional, its objective is to determine bacterial resistance patterns of Staphylococcus spp from the antibiogram records carried out in the Medilab-Medihospital Clinical Laboratory from 2018 to 2020. In addition, 86 positive cultures were isolated for Staphylococcus spp, the studied showed that Staphylococcus aureus and Staphylococcus epidermidis are the most frequent in the outpatient area with 71.43% and 78.40% respectively with predominance in secretion samples with 77.6% and 67.6%. The resistance profile of Staphylococcus aureus against the antibiotics tested in the microbiology laboratory are the following: penicillin (87%), oxacillin (81.50%) and erythromycin (64.6%); while that of Staphylococcus epidermidis was: penicillin (75%), oxacillin (66.7%), erythromycin (62.9%), and clindamycin (52.8%). It is concluded that in both groups of microorganisms they express phenotypes of resistance to oxacillin, penicillin and erythromycin, besides sensitivity to vancomycin and linezolid and variable susceptibility to the rest of the antibiotics evaluated.La resistencia bacteriana frente a los antibióticos es uno de los problemas más grandes de salud pública a nivel mundial. Esto nos dificulta controlar las enfermedades infecciosas causadas por microorganismos bacterianos ya que genera fallo terapéutico, alarga los tratamientos y aumenta costes en la atención de la salud. El microorganismo Staphylococcus spp, es uno de los grupos bacterianos más estudiados debido a su importancia clínica y las altas tasas de resistencia que presenta frente a los antibióticos. La especie más importante es Staphylococcus aureus considerándose la más patógena seguida de los estafilococos coagulasa negativos que actúan como patógenos oportunistas. El presente estudio es de tipo descriptivo y transversal, tiene como objetivo determinar patrones de resistencia bacteriana de Staphylococcus spp de los registros de antibiogramas realizados en el Laboratorio Clínico Medilab-Medihospital desde el año 2018 hasta el 2020. Se aislaron 86 cultivos positivos para Staphylococcus spp, siendo Staphylococcus aureus y Staphylococcus epidermidis los más frecuentes en el área de consulta externa con el 71,43% y 78,40% respectivamente y predominando en muestras de secreciones con el 77,6% y 67,6%. El perfil de resistencia de Staphylococcus aureus frente a los antibióticos ensayados en el laboratorio de microbiología son: penicilina (87 %), oxacilina (81,50%) y eritromicina (64,6%); mientras que el de Staphylococcus epidermidis fue: penicilina (75 %), oxacilina (66,7%), eritromicina (62,9%) y clindamicina (52,8%). Se concluye que en ambos grupos de microorganismos expresan fenotipos de resistencia a oxacilina, penicilina y eritromicina, sensibilidad a vancomicina y linezolid y susceptibilidad variable al resto de antibióticos evaluadosLojaDelgado, Iliana Alicia2022-02-11T20:44:23Z2022-02-11T20:44:23Z2022-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesis74 p.application/pdfhttps://dspace.unl.edu.ec/jspui/handle/123456789/24548spahttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Nacional de Lojainstname:Universidad Nacional de Lojainstacron:UNL2025-05-02T17:08:57Zoai:dspace.unl.edu.ec:123456789/24548Institucionalhttps://dspace.unl.edu.ec/Universidad públicahttps://unl.edu.ec/https://dspace.unl.edu.ec/oaiEcuador***opendoar:02025-05-02T17:08:57falseInstitucionalhttps://dspace.unl.edu.ec/Universidad públicahttps://unl.edu.ec/https://dspace.unl.edu.ec/oai*Ecuador***opendoar:02025-05-02T17:08:57Repositorio Universidad Nacional de Loja - Universidad Nacional de Lojafalse
spellingShingle Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
Castillo Vélez, Ana Janela
LABORATORIO CLÍNICO
PATRONES DE RESISTENCIA BACTERIANA
STAPHYLOCOCCUS AUREUS
ANTIBIÓTICOS
status_str publishedVersion
title Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
title_full Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
title_fullStr Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
title_full_unstemmed Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
title_short Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
title_sort Patrones de resistencia bacteriana en Staphylococcus spp de Medilab-Medihospital, Loja 2018- 2020
topic LABORATORIO CLÍNICO
PATRONES DE RESISTENCIA BACTERIANA
STAPHYLOCOCCUS AUREUS
ANTIBIÓTICOS
url https://dspace.unl.edu.ec/jspui/handle/123456789/24548