Intoxicación por órganos fosforados: niveles de colinesterasa y uso de ventilacion mecánica en pacientes ingresados en unidad de cuidados intensivos del Hospital Regional Isidro Ayora en el periodo enero-julio 2012

Organophosphates are phosphoric acid esters and organic derivatives with esterase inhibitory action, mainly cholinesterase. The main organophosphates are pesticides (malathion, parathion, dimethoate, fenthion, propoxur and diclofenotion) which are useful for pest control in the domestic, agricultural and veterinary top positions in acute poisoning. Our environment is recognized as a health risk, from the earliest stages of history, there have been well-documented outbreaks of "poisoning" by organic or inorganic chemical substance accidentally or intentionally. Accidental poisonings, unintentional overdoses in adults individually or collectively, organophosphates are still observed in our city hospitals. It is used in agriculture, horticulture and domestic, in presenting this poisoning sprayers, harvesters, ingestion of contaminated food and intentional ingestion. Intoxication routes including oral, inhalation or dermal absorption. This study was conducted at Hospital "Isidro Ayora" during the period January-July 2012 which was descriptive and cross-sectional, which involved 22 patients, obtaining a survey record low according to the main factors: age, sex and data collection from medical records, to identify cholinesterase levels and use of mechanical ventilation in patients admitted to the Intensive Care Unit of this institution. 68% of the patients were male, in 100% of cases of digestive absorption was toxic, with 82% of accidental nature. They specified mechanical ventilation, 64% of patients, of which 50% remained in the same 0-7 days and 36% of 7-14 days. In 77% of the name is unknown toxic. 100% of patients had values <1000U / L Cholinesterase your income. 55% remained hospitalized in ICU for 7-14 days and 36% of 0-7 days, there was 0% mortality. KEYWORDS: organophosphate poisoning, mechanical ventilation, Cholinesterase.

• Autor Principal: Sanmartín Herrera, Carlos Julio (author)
• Formato: bachelorThesis
• Idioma: spa
• Publicado: 2011
• Acceso en liña: http://dspace.unl.edu.ec/jspui/handle/123456789/8051