Patrones de resistencia bacteriana en Enterobacteriaceae procedentes de pacientes hospitalizados en la clínica MedilabMedihospital de Loja, 2018- 2020
Bacterial resistance is the ability of the bacteria to evade the action mechanisms of various antibiotics, it is considered one of the biggest problem in the public health, since the consequences are the failure of antimicrobial therapies, increased morbidity and mortality and the increased in the c...
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| Médium: | bachelorThesis |
| Jazyk: | spa |
| Vydáno: |
2022
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| Témata: | |
| On-line přístup: | https://dspace.unl.edu.ec/jspui/handle/123456789/24835 |
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| Shrnutí: | Bacterial resistance is the ability of the bacteria to evade the action mechanisms of various antibiotics, it is considered one of the biggest problem in the public health, since the consequences are the failure of antimicrobial therapies, increased morbidity and mortality and the increased in the costs of medical attention, for this reason the purpose of the present quantitative and retrospective-cross-sectional research work was to determine resistance patterns of Enterobacteriaceae in samples of patients from hospitalization and surgery who attended the Medilab-Medihospital Clinic. in the period 2018-2020. The study included 82 samples, of which E. coli was the most frequently isolated microorganism (69.5%), followed by K. pneumoniae (88.5%), the largest number of bacterial isolates was obtained in samples of urine (69.5%), followed by secretions (18.3%). In the resistance pattern, it was determined that K. pneumoniae, S. marcsensens, E. cloacae and E. coli presented percentages greater than the 70% in their resistance patterns with more than 7 antibiotics, the patterns determined in the prepandemic and pandemic periods showed variations in percentages of resistance to cephalosporins, aminoglycosides, fluoroquinolones, carbapenems, and sulfonamides in species of E. coli, K. oxytoca, P. mirabilis, and E. cloacae. Extended-spectrum bealactamase-producing strains represented the 36.8% of E. coli isolates and the 50% of K. oxytoca; The 50% of S. marcescens strains are carbapenemase producers. Consequently, the creation of policies that establish the rational management of antibiotics in the Medilab-Medihospital clinic as an essential tool in the control of bacterial resistance is suggested |
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