Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria
Drago’s Blood (Croton lechleri) is a plant resin widely used for its therapeutic properties in traditional medicine, particularly as a wound healer, antimicrobial, and anti-inflammatory agent. This study aimed to chemically characterize its compounds to assess their potential use in veterinary medic...
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Materiálatiipa: | bachelorThesis |
Giella: | spa |
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2025
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Fáttát: | |
Liŋkkat: | https://dspace.unl.edu.ec/jspui/handle/123456789/32175 |
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author | Guaillas Zhondo, Benito Fabián |
author_facet | Guaillas Zhondo, Benito Fabián |
author_role | author |
collection | Repositorio Universidad Nacional de Loja |
dc.contributor.none.fl_str_mv | Vacacela Ajila, Wilmer Augusto |
dc.creator.none.fl_str_mv | Guaillas Zhondo, Benito Fabián |
dc.date.none.fl_str_mv | 2025-03-25T13:33:48Z 2025-03-25T13:33:48Z 2025-03-25 |
dc.format.none.fl_str_mv | 30 p. application/pdf |
dc.identifier.none.fl_str_mv | https://dspace.unl.edu.ec/jspui/handle/123456789/32175 |
dc.language.none.fl_str_mv | spa |
dc.publisher.none.fl_str_mv | Loja |
dc.rights.none.fl_str_mv | http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ info:eu-repo/semantics/openAccess |
dc.source.none.fl_str_mv | reponame:Repositorio Universidad Nacional de Loja instname:Universidad Nacional de Loja instacron:UNL |
dc.subject.none.fl_str_mv | SANGRE DE DRAGO COMPUESTOS BIOACTIVOS PROPIEDADES TERAPEUTICAS |
dc.title.none.fl_str_mv | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/bachelorThesis |
description | Drago’s Blood (Croton lechleri) is a plant resin widely used for its therapeutic properties in traditional medicine, particularly as a wound healer, antimicrobial, and anti-inflammatory agent. This study aimed to chemically characterize its compounds to assess their potential use in veterinary medicine through thin-layer and column chromatography. Samples were collected in the parish of Nuevo Paraíso, Nangaritza Canton, Zamora Chinchipe Province, and analyzed using thin-layer chromatography (TLC) and column chromatography. Seven bioactive compounds were identified: proanthocyanidins (polymeric flavonoids) with a retention factor (Rf) of 0.2 to 0.4, taspine (alkaloid) with an Rf of 0.5 to 0.6, catechins (monomeric flavonoids) with an Rf of 0.3 to 0.5, gallic acid (phenolic acid) with an Rf of 0.4 to 0.6, terpenes (mono- and sesquiterpenes) with an Rf of 0.7 to 0.8, β-sitosterol (sterol) with an Rf of 0.6 to 0.7, and lignans (dimethylcedrusin) with an Rf of 0.5 to 0.7. Column chromatography enabled the separation of these compounds into seven fractions, confirming their presence and therapeutic relevance. The identified bioactive properties include wound-healing, anti-inflammatory, antimicrobial, antioxidant, and antiviral effects, with taspine, lignans, proanthocyanidins, β-sitosterol, catechins, and gallic acid being particularly noteworthy. These findings support the potential of Drago’s blood in veterinary medicine, solidifying it as a valuable natural resource for developing new therapeutic alternatives. |
eu_rights_str_mv | openAccess |
format | bachelorThesis |
id | UNL_6972a150a8dc5b61b058afd06f6f7699 |
instacron_str | UNL |
institution | UNL |
instname_str | Universidad Nacional de Loja |
language | spa |
network_acronym_str | UNL |
network_name_str | Repositorio Universidad Nacional de Loja |
oai_identifier_str | oai:dspace.unl.edu.ec:123456789/32175 |
publishDate | 2025 |
publisher.none.fl_str_mv | Loja |
reponame_str | Repositorio Universidad Nacional de Loja |
repository.mail.fl_str_mv | * |
repository.name.fl_str_mv | Repositorio Universidad Nacional de Loja - Universidad Nacional de Loja |
repository_id_str | 0 |
rights_invalid_str_mv | http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ |
spelling | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina VeterinariaGuaillas Zhondo, Benito FabiánSANGRE DE DRAGOCOMPUESTOS BIOACTIVOSPROPIEDADES TERAPEUTICASDrago’s Blood (Croton lechleri) is a plant resin widely used for its therapeutic properties in traditional medicine, particularly as a wound healer, antimicrobial, and anti-inflammatory agent. This study aimed to chemically characterize its compounds to assess their potential use in veterinary medicine through thin-layer and column chromatography. Samples were collected in the parish of Nuevo Paraíso, Nangaritza Canton, Zamora Chinchipe Province, and analyzed using thin-layer chromatography (TLC) and column chromatography. Seven bioactive compounds were identified: proanthocyanidins (polymeric flavonoids) with a retention factor (Rf) of 0.2 to 0.4, taspine (alkaloid) with an Rf of 0.5 to 0.6, catechins (monomeric flavonoids) with an Rf of 0.3 to 0.5, gallic acid (phenolic acid) with an Rf of 0.4 to 0.6, terpenes (mono- and sesquiterpenes) with an Rf of 0.7 to 0.8, β-sitosterol (sterol) with an Rf of 0.6 to 0.7, and lignans (dimethylcedrusin) with an Rf of 0.5 to 0.7. Column chromatography enabled the separation of these compounds into seven fractions, confirming their presence and therapeutic relevance. The identified bioactive properties include wound-healing, anti-inflammatory, antimicrobial, antioxidant, and antiviral effects, with taspine, lignans, proanthocyanidins, β-sitosterol, catechins, and gallic acid being particularly noteworthy. These findings support the potential of Drago’s blood in veterinary medicine, solidifying it as a valuable natural resource for developing new therapeutic alternatives.La sangre de drago (Croton lechleri) es una resina vegetal ampliamente utilizada por sus propiedades terapéuticas en la medicina tradicional, especialmente como cicatrizante, antimicrobiano y antiinflamatorio. Esta investigación tuvo como objetivo caracterizar químicamente sus compuestos para evaluar su potencial uso en medicina veterinaria mediante cromatografía de capa fina y de columna. Se recolectaron muestras en la parroquia de Nuevo Paraíso, Cantón Nangaritza, provincia de Zamora Chinchipe, y se analizaron mediante cromatografía de capa fina (TLC) y cromatografía de columna. Se identificaron siete compuestos bioactivos: proantocianidinas (flavonoides poliméricos) con un factor de retención (Rf) de 0.2 a 0.4, taspina (alcaloide) con un Rf de 0.5 a 0.6, las catequinas (flavonoides monoméricos) con Rf de 0.3 a 0.5, ácido gálico (ácido fenólico) con Rf de 0.4 a 0.6, terpenos (mono y sesquiterpenos) con Rf de 0.7 a 0.8, el β-sitosterol (esterol) con Rf de 0.6 a 0.7, y lignanos (dimetileedrusina) con Rf 0.5 a 0.7. La cromatografía de columna permitió la separación de estos compuestos en siete fracciones, confirmando su presencia y relevancia terapéutica. Las propiedades bioactivas identificadas incluyen efectos cicatrizantes, antiinflamatorios, antimicrobianos, antioxidantes y antivirales, destacándose la taspina, los lignanos, las proantocianidinas, el β-sitosterol, las catequinas y el ácido gálico. Estos hallazgos respaldan el potencial de la sangre de drago en la medicina veterinaria, consolidándola como un recurso natural valioso para el desarrollo de nuevas alternativas terapéuticas.LojaVacacela Ajila, Wilmer Augusto2025-03-25T13:33:48Z2025-03-25T13:33:48Z2025-03-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesis30 p.application/pdfhttps://dspace.unl.edu.ec/jspui/handle/123456789/32175spahttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Nacional de Lojainstname:Universidad Nacional de Lojainstacron:UNL2025-05-02T17:25:10Zoai:dspace.unl.edu.ec:123456789/32175Institucionalhttps://dspace.unl.edu.ec/Universidad públicahttps://unl.edu.ec/https://dspace.unl.edu.ec/oaiEcuador***opendoar:02025-07-27T13:59:57.271826trueInstitucionalhttps://dspace.unl.edu.ec/Universidad públicahttps://unl.edu.ec/https://dspace.unl.edu.ec/oai*Ecuador***opendoar:02025-07-27T13:59:57.271826Repositorio Universidad Nacional de Loja - Universidad Nacional de Lojatrue |
spellingShingle | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria Guaillas Zhondo, Benito Fabián SANGRE DE DRAGO COMPUESTOS BIOACTIVOS PROPIEDADES TERAPEUTICAS |
status_str | publishedVersion |
title | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
title_full | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
title_fullStr | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
title_full_unstemmed | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
title_short | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
title_sort | Caracterización química de la sangre de drago (Croton lechleri) para su potencial uso en Medicina Veterinaria |
topic | SANGRE DE DRAGO COMPUESTOS BIOACTIVOS PROPIEDADES TERAPEUTICAS |
url | https://dspace.unl.edu.ec/jspui/handle/123456789/32175 |