Fenotipificación de resistencia bacteriana en agentes etiológicos de infección de vías urinarias en pacientes embarazadas del Centro de Salud Universitario de Motupe

At present, the mechanisms of bacterial resistance to antibiotics constitute a health problem and a global concern due to the threats that this represents for all people regardless of gender or age, particularly for vulnerable groups such as pregnant patients, who can develop mechanisms that prevent...

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Bibliographic Details
Main Author: Carchi Flores, María Belén (author)
Format: bachelorThesis
Language:spa
Published: 2022
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Online Access:https://dspace.unl.edu.ec/jspui/handle/123456789/25926
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Summary:At present, the mechanisms of bacterial resistance to antibiotics constitute a health problem and a global concern due to the threats that this represents for all people regardless of gender or age, particularly for vulnerable groups such as pregnant patients, who can develop mechanisms that prevent antibiotics from exerting their action, generating complications with maternal and fetal risk such as threatened abortion, rupture of membranes, preterm delivery and low birth weight, that is why that the following project lies in determining the bacterial resistance of etiological agents of urinary tract infection in pregnant patients of the Motupe University Health Center, being of total support for medical diagnosis, reducing reinfections and maternal and fetal morbidity and mortality rates, avoiding the spread of this phenomenon that is currently alarming. The study was of a non-experimental quantitative approach, with a descriptive cross-sectional design, where 126 urine samples from pregnant patients were examined, of which 19 urine cultures were positive and were analyzed by phenotypic methods through antibiogram. Two resistance mechanisms were determined among the isolates, one of Escherichia coli producing Extended Spectrum Beta-lactamases (ESBL) and Staphylococcus aureus with resistance to Macrolides, Lincosamides and Streptogramins (MLS) in 5.26% for both cases. Resistance to ampicillin was found to be more prevalent in gram-negative etiological agents and in grampositive agents to erythromycin and clindamycin