Eficacia de la vía oral e intravaginal del misoprostol en pacientes con aborto diferido menores de doce semanas de gestación.

Deferred abortion is a condition characterized by retention in the uterine cavity of an embryo or fetus died several days or weeks and the drug to give optimal global treatment is the misoprostol, since in more than eighty countries is recorded . Objective: To compare which of the routes of administration of misoprostol (oral vs. intravaginal) for cervical ripening in these patients was the most appropriate in terms of dosage, adverse effects and ejection time. Materials and Methods: A descriptive, prospective study in which the efficacy of misoprostol was determined in patients with missed abortion under twelve weeks gestation who were treated in the emergency department of the Civil Hospital San Vicente de Paul from January to July 2016. the study included 60 patients, of which 30 were given misoprostol orally and the other 30, misoprostol intravaginally participated. Results: nulliparous patients had a higher incidence of abortion and reported no history of previous abortions. Nine patients required new dosage Miso-VO group, on the other hand, Miso-IV group, 23 required another dose. By ultrasonographic corroboration, after 72 hours of administration of misoprostol either orally or vaginally, 70% (42 of 60 patients) of the patients have completely evacuated the uterine cavity. 30% of patients required surgical intervention. 26.4% of patients who were administered Miso-VO showed moderate abdominal pain on the VAS scale at 8 hours, and 80% of Miso-IV patients have abdominal pain moderate to severe within first 4 to 8 hours. The adverse effect highlight for patients who were given misoprostol either orally by ovaginal was nausea. The fourth and fifth weeks are the most effective for treatment with misoprostol, with 48.3% (29 of 60 patients). Conclusion: Miso-VO is more effective than the Miso-IV, since it requires fewer doses for the desired effect. Key words: Oral and intravaginal misoprostol, missed abortion, uterine evacuation dosing.

• Autor Principal: Mendoza Taday, Alcides Fabricio (author)
• Formato: bachelorThesis
• Idioma: spa
• Publicado: 2016
• Subjects: ABORTO; ETIOLOGÍA; DIAGNÓSTICO
• Acceso en liña: http://dspace.unl.edu.ec/jspui/handle/123456789/17079