Tiempo de protrombina TP y tiempo parcial de tromboplastina TPT y su relación con la comunidad terapéutica Centsadic de la ciudad de Loja
Abuse and dependence of psychoactive substances are commonly considered one of the most important social problems locally, nationally and globally, because each year the number of mortality and morbidity increases by various diseases caused by the consumption of these toxic substances, especially pr...
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| Format: | bachelorThesis |
| Idioma: | spa |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | http://dspace.unl.edu.ec/jspui/handle/123456789/13757 |
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Afegir etiqueta | Sumari: | Abuse and dependence of psychoactive substances are commonly considered one of the most important social problems locally, nationally and globally, because each year the number of mortality and morbidity increases by various diseases caused by the consumption of these toxic substances, especially problems with the liver. The liver is the responsible for the detoxification of harmful substances in the body; it plays an important role in the synthesis of proteins and metabolites, especially coagulation proteins; which may be altered due to the continuous and long-term consumption of psychoactive substances. According to this problem, the present descriptive cross-sectional study focuses on determining the prothrombin and thromboplastin times in relation with substance use in the population of the therapeutic community Salvando al Adicto "CENTSADIC" because they are the most vulnerable people of developing certain diseases due to consumption of these substances. This research was carried out to evaluate the liver synthetic function and to evaluate hemostatic abnormalities in people with liver disorders. For the study a total of 54 samples of admitted people were collected then they were analyzed using the turbidimetric method for determining the PT and PTT times and to relate the above results with the time of psychoactive substances consumption, to develop this it was necessary to apply a survey to each participant to be aware of the years of using these substances. According to obtained data of this research, a total of 7.41% of admitted people presented an altered TP, where 75% of these cases presented the predisposing factor of psychoactive substances consumption of 5 years or more, while TPT was found between the normal values in 100% of admitted people. Keywords: Psychoactive substances, prothrombin time, thromboplastin time. |
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