Efecto citotóxico del extracto etanólico de hojas de Annona cherimola en una línea celular de cáncer de pulmón humano en medio de cultivo con pH neutro.

Since ancient plants have been very helpful to humans both for food and for healing in order to combat various diseases of man resource, and even today are studied and analyzed so that they have been grouped the properties they own. Medicinal plants are important to pharmacology and development of new medicines (Lock, 2010). It has been found that the Annona cherimola has antitumor properties and possess cytotoxic compounds such as cyclopeptides, heptapeptide, alkaloids and acetogenins have produced a cytotoxic effect on other tumor lines already tested; acetogenins are secondary potent and specific mitochondrial complex reducing may reduce neoplastic cell proliferation inhibitory metabolites (Schile. Et al, 2009). This research aims to determine the cytotoxic effect that produces ethanol extract from the leaves of Annona cherimola against the cell line of lung cancer, the same who was executed in the laboratories of the Biotechnology Center at the National University of Loja. The research has an experimental design, prospective. The techniques used for the cytotoxic cell proliferation analysis were measured by the confluence per unit time; and cell viability was done using the dye exclusion method of trypan blue and cell counting was performed per unit time. The results were that the extract of Annona cherimola have a viability of 15.1% and 62.1% cytotoxic activity against cell lung cancer line KEYWORDS: cytotoxic effect, Annona cherimola, Lung Cancer, proliferation, viability.

• 主要作者: Muñoz Yunga, Verónica Cristina (author)
• 格式: bachelorThesis
• 出版: 2016
• 主題: MEDICINA TRADICIONAL; PLANTAS MEDICINALES; CÁNCER - PULMÓN
• 在線閱讀: http://dspace.unl.edu.ec/jspui/handle/123456789/10130