Análisis del pH salival en pacientes oncológicos adultos bajo quimioterapia que acuden a SOLCA - LOJA en el periodo Septiembre - Diciembre 2022
Saliva is an aqueous solution with a complex alkaline reaction, viscosity originating from the secretion of major and minor salivary glands. It consists of 99% water and 1% organic and inorganic molecules. The normal salivary pH ranges from approximately 6.5 to 7, varying from acidic to basic. Saliv...
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| Médium: | bachelorThesis |
| Jazyk: | spa |
| Vydáno: |
2023
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| Témata: | |
| On-line přístup: | https://dspace.unl.edu.ec/jspui/handle/123456789/28373 |
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Přidat tag | Shrnutí: | Saliva is an aqueous solution with a complex alkaline reaction, viscosity originating from the secretion of major and minor salivary glands. It consists of 99% water and 1% organic and inorganic molecules. The normal salivary pH ranges from approximately 6.5 to 7, varying from acidic to basic. Salivary pH can be altered in patients undergoing chemical therapies affecting the salivary glands, consequently impacting saliva production and pH variations. Therefore, the present research is aimed to determine changes in salivary pH in adult oncology patients undergoing chemotherapy at the Cancer Institute Solca in the city of Loja. The study also aimed to explore the relationship between the number of treatment cycles, dosage, and antineoplastic drugs with salivary pH variations. Through an analytical, cross-sectional casecontrol study involving 16 patients undergoing chemotherapy, with a four-month follow-up, using the dental history elaborated and approved for the research project to provide care for patients at the Solca Nucleus Loja between September to December 2022. The obtained results revealed that patients undergoing chemotherapy had a normal salivary pH range of 6 to 7 prior to oncology treatment, accounting for 50% and 43.8% of the population, respectively. During treatment, salivary pH values were in the range of 7 to 8, comprising 37.5% and 62.5% of the population, signifying an increase of 1 to 2 pH units from the initial values, indicating alkalization of the pH. Post-oncology treatment, salivary pH ranged from 7 to 6, accounting for 81.3% and 12.5% of cases, respectively, reflecting a decrease of 1 to 2 pH units, resulting in a neutral pH within normal values. Additionally, it was determined that no significant differences existed concerning the number of treatment cycles, antineoplastic drugs, and dosages with salivary pH variations. In conclusion, changes in salivary pH occur during distinct stages of oncology treatment follow-up. However, it cannot be confirmed or refuted that the number of treatment cycles, dosages, and antineoplastic drugs cause these substantial pH changes in chemotherapy patients |
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