Estudio comparativo de las propiedades antimicrobianas del extracto de arándano frente a la clorhexidina al 0,12%, en el efecto inhibitorio de un periodontopatógeno (Porphyromonas Gingivalis) estudio in vitro
Nowadays, the usage of medicinal plants as an alternative method is favorable since the different drugs are manufactured based on compounds found in plants and their fruits. Every day the need to investigate these active principles is growing, testing the herbal extracts effectively in the treatment...
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| Format: | bachelorThesis |
| Jezik: | spa |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | http://dspace.unl.edu.ec/jspui/handle/123456789/23422 |
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Dodaj oznaku | Sažetak: | Nowadays, the usage of medicinal plants as an alternative method is favorable since the different drugs are manufactured based on compounds found in plants and their fruits. Every day the need to investigate these active principles is growing, testing the herbal extracts effectively in the treatment and prevention of oral diseases. The objective of this in vitro study is to compare the antimicrobial efficacy of the blueberry extract in different concentrations against chlorhexidine implemented in Porphyromones Gingivalis as the leading etiological pathogen of periodontal disease. The design was of an experimental in vitro cross-sectional type. Through the maceration method, were processed Biloxi Blueberry extracts obtaining pure concentration. Afterward, was developed the culture medium with enriched blood agar by activating Porphyromones Gingivalis strains, proceeding to utilize discs permeated with the substances, by employing the Kirby Bauer's method of treating the P biofilms. Gingivalis biofilms and leaving them to act in 24 and 96 hours in 1:1 concentration of pure extract and solutions from this, obtaining reference values of the minimum inhibitory concentration against the effectiveness of chlorhexidine. This research concluded that blueberry plays an essential function in the alternative use of pure extracts with a high content of phenolic compounds and can act as an agent capable of modifying the virulent action of a bacterium such as P. Gingivalis, with positive outcomes in contrast to the chlorhexidine at 0.12%. Keywords: Phenols; Inhibitory Halos; Biofilms; Periodontal Disease. |
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