Concentración mínima inhibitoria de ceftriaxone frente a Escherichia coli spp aislada en urocultivos de pacientes de consulta externa del Hospital Militar Brigada Nro 7 de la ciudad de Loja
The minimum inhibitory concentration (MIC) is the lowest concentration of antimicrobial capable of inhibiting bacterial growth in a period of time. The Escherichia. Coli spp is a Gram-negative bacterium that causes one of the most common infections of urinary tract at Community level that affect hum...
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| Format: | bachelorThesis |
| Sprog: | spa |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | http://dspace.unl.edu.ec/jspui/handle/123456789/10507 |
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Tilføj Tag | Summary: | The minimum inhibitory concentration (MIC) is the lowest concentration of antimicrobial capable of inhibiting bacterial growth in a period of time. The Escherichia. Coli spp is a Gram-negative bacterium that causes one of the most common infections of urinary tract at Community level that affect humans and is become more and more resistant what has become a global health problem. Tighter control, to ensure the appropriate use of antimicrobials is necessary and to prevent the emergence and spread of bacterial resistance. Therefore the purpose of this research was to determine the MIC of ceftriaxone against E. coli in urine cultures outpatient Brigade Military Hospital No. 7 in the city of Loja. A descriptive cross-sectional study applies 106 urine cultures were processed of which 50 were positive for further growth had 100 000 CFU / ml, and of these 34 strains they were positive for E. coli spp (68%); Klebsiella pneumoniae (12%); Pseudomonas aeruginosa (8%); Proteus mirabilis, Proteus vulgaris, Klebsiella oxytoca. All strains were isolated and identified and processed according to established protocols with (4%). All strains were isolated and identified and processed according to established protocols. Susceptibility testing was performed by the macrodilution method in triplicate; for each positive and negative control sample was used; reference of this study, a control strain and ATCC.25922 determining the minimum bactericidal concentration (MBC) was used. It is the minimum concentration of antibiotic to kill the bacteria in vitro. The sensitivity demonstrated that E. coli front ceftriaxone was 62% (≤1 ug /ml) sensitive, 9% (=2 ug /ml) intermediate and 29% (≥4 ug /ml) resistant, with reference to the 2015 CLSI. Key words: Minimum inhibitory concentration (MIC); ceftriaxone; Escherichia coli. |
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