Desarrollo de formulaciones fito - cosméticas antioxidantes empleando como sustancia activa el extracto seco de Cinchona pubescens Vahl, Rubiaceae (Cascarilla)
This study aimed to assess the species Cinchona pubescens Vahl, known as "scale" as a raw material for cosmetics evaluating the properties and antioxidant components, both in solids, as in cosmetic formulations. The species is widely published in the Ecuadorian territory and its high adapt...
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| Format: | masterThesis |
| Langue: | spa |
| Publié: |
2015
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| Accès en ligne: | https://dspace.ups.edu.ec/handle/123456789/9377 |
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Ajouter un tag | Résumé: | This study aimed to assess the species Cinchona pubescens Vahl, known as "scale" as a raw material for cosmetics evaluating the properties and antioxidant components, both in solids, as in cosmetic formulations. The species is widely published in the Ecuadorian territory and its high adaptability has become an invasive species making relevant initiate investigations with a view to industrial use. The phenolic compound concentration in the extract and flavonoids were respectively 30 mg GAE / g Hyp 2 mg / g. Flavonoids characterized by the HP-TLC methodology were: apigenin, quercetin, kaempferol and catechin. The antioxidant activity of the extract and assessed by the DPPH ABTS spectrophotometric methods gave the following values: IC50 (DPPH) 0.0466 mg / mL and the IC50 (ABTS) 0.082 mg / ml. In cosmetic formulations evaluated by the methodology Fotoquimioluminiscencia a significantly increased antioxidant potential when compared to the base formula is observed, up to 15 times higher concentrations of the assay, in all cases (gel or cream), the behavior turned higher as compared to a positive pattern formulated with dry extract of Camellia sinensis. |
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