Optimización del proceso de extracción hidroalcohólica a partir de chillangua (eryngium foetidum l), en función del contenido de polifenoles y actividad antioxidante.

The objective of this study was the extraction of the crude drug from chillangua (Eryngium foetidum L), the leaves were taken into account to carry out the study, therefore, the leaves were dehydrated in a forced air oven for 4 days. at 40° C. From this analysis, on the one hand, the phytochemical profile was determined and through the optimized extract, the antioxidant capacity was determined. The Design Expert 8.0.6 program determined 27 runs with different variables such as; stanol concentration (60%, 75%, 90%), extraction time (6h, 15h, 24h) and temperature (30°C, 45°C, 60°C). According to the analysis of the phytochemical profile carried out, the metabolites that chillangua leaves (Eryngium foetidum L) have are; saponins, phenolic compounds, quinones / benzoquinones, flavonoids, bitter principles, mucilages, triterpenes / steroids, lactone grouping, fatty compounds, alkaloids and catechins. On the other hand, the polyphenol content and antioxidant capacity of the different experimental runs were determined, subjecting the crude drug to a hydroalcoholic solution. The numerical optimization of the hydroalcoholic extraction was compared with the experimental values of total polyphenols (61.53 mg/g) and antioxidant capacity (325.48 μmolFe2+/g), with those obtained in the optimization by means of the program, which were ; total polyphenols (60.553 mg/g) and antioxidant activity (324.456 μmolFe2+/g). The values achieved through experimentation are higher than the values of numerical optimization.

• Autor principal: Quevedo Barreto, Luci Angelita (author)
• Formato: masterThesis
• Idioma: spa
• Publicado em: 2022
• Assuntos: EXTRACCIÓN; POLIFENOLES; ANTIOXIDANTE; CHILLANGUA; AGROINDUSTRIA
• Acesso em linha: http://repositorio.utc.edu.ec/handle/27000/9077