Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model
Keratoconus is an eye disease that distorts the shape of the cornea. This study aimed to analyze the effect of an increase in intraocular pressure applied to eyes with different severity of keratoconus disease using patient-specific models. Finite element models of the normal eye, eye with keratocon...
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| Natura: | article |
| Lingua: | eng |
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2023
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| Accesso online: | https://www.mdpi.com/2076-3417/13/22/12308 https://hdl.handle.net/20.500.14809/6916 |
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| author | Sánchez-Real, Emily |
| author2 | Otuna-Hernández, Diego Fajardo-Cabrera, Alisson Davies-Alcívar, Rosemary Madrid-Pérez, Mario Cadena-Morejón, Carolina Almeida-Galárraga, Diego Guevara, César Tirado-Espín, Andrés Villalba-Meneses, Fernando |
| author2_role | author author author author author author author author author |
| author_facet | Sánchez-Real, Emily Otuna-Hernández, Diego Fajardo-Cabrera, Alisson Davies-Alcívar, Rosemary Madrid-Pérez, Mario Cadena-Morejón, Carolina Almeida-Galárraga, Diego Guevara, César Tirado-Espín, Andrés Villalba-Meneses, Fernando |
| author_role | author |
| collection | Repositorio Universidad Tecnológica Indoamérica |
| dc.creator.none.fl_str_mv | Sánchez-Real, Emily Otuna-Hernández, Diego Fajardo-Cabrera, Alisson Davies-Alcívar, Rosemary Madrid-Pérez, Mario Cadena-Morejón, Carolina Almeida-Galárraga, Diego Guevara, César Tirado-Espín, Andrés Villalba-Meneses, Fernando |
| dc.date.none.fl_str_mv | 2023 2024-07-28T20:57:05Z 2024-07-28T20:57:05Z |
| dc.identifier.none.fl_str_mv | https://www.mdpi.com/2076-3417/13/22/12308 https://hdl.handle.net/20.500.14809/6916 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Applied Sciences (Switzerland). Open AccessVolume 13, Issue 22 |
| dc.rights.none.fl_str_mv | https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio Universidad Tecnológica Indoamérica instname:Universidad Tecnológica Indoamérica instacron:UTI |
| dc.title.none.fl_str_mv | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Keratoconus is an eye disease that distorts the shape of the cornea. This study aimed to analyze the effect of an increase in intraocular pressure applied to eyes with different severity of keratoconus disease using patient-specific models. Finite element models of the normal eye, eye with keratoconus, and eye with keratoglobus were constructed. The loading conditions considered the intraocular pressure increment as well as their physiological intraocular pressure. The analysis was performed with distinct materials for normal and keratoconic eyes. The finite element analysis revealed differences in the three models in terms of their deformation and maximum principal stress, and differences were observed in corneal curvature and thickness. These findings could enhance research in the biomechanical area, leading to more successful treatment options and a more individualized approach in the field of practical ophthalmology. Further investigation with larger sample sizes and more precise data on eye material would allow us to evaluate whether these disparities could inform the diagnosis of keratoconus. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UTI_a05fbf45a993fcf881c94f4a74e4f61d |
| instacron_str | UTI |
| institution | UTI |
| instname_str | Universidad Tecnológica Indoamérica |
| language | eng |
| network_acronym_str | UTI |
| network_name_str | Repositorio Universidad Tecnológica Indoamérica |
| oai_identifier_str | oai:repositorio.uti.edu.ec:20.500.14809/6916 |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Applied Sciences (Switzerland). Open AccessVolume 13, Issue 22 |
| reponame_str | Repositorio Universidad Tecnológica Indoamérica |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio Universidad Tecnológica Indoamérica - Universidad Tecnológica Indoamérica |
| repository_id_str | 0 |
| rights_invalid_str_mv | https://creativecommons.org/licenses/by/4.0/ |
| spelling | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric ModelSánchez-Real, EmilyOtuna-Hernández, DiegoFajardo-Cabrera, AlissonDavies-Alcívar, RosemaryMadrid-Pérez, MarioCadena-Morejón, CarolinaAlmeida-Galárraga, DiegoGuevara, CésarTirado-Espín, AndrésVillalba-Meneses, FernandoKeratoconus is an eye disease that distorts the shape of the cornea. This study aimed to analyze the effect of an increase in intraocular pressure applied to eyes with different severity of keratoconus disease using patient-specific models. Finite element models of the normal eye, eye with keratoconus, and eye with keratoglobus were constructed. The loading conditions considered the intraocular pressure increment as well as their physiological intraocular pressure. The analysis was performed with distinct materials for normal and keratoconic eyes. The finite element analysis revealed differences in the three models in terms of their deformation and maximum principal stress, and differences were observed in corneal curvature and thickness. These findings could enhance research in the biomechanical area, leading to more successful treatment options and a more individualized approach in the field of practical ophthalmology. Further investigation with larger sample sizes and more precise data on eye material would allow us to evaluate whether these disparities could inform the diagnosis of keratoconus.Applied Sciences (Switzerland). Open AccessVolume 13, Issue 222024-07-28T20:57:05Z2024-07-28T20:57:05Z2023info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.mdpi.com/2076-3417/13/22/12308https://hdl.handle.net/20.500.14809/6916enghttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Tecnológica Indoaméricainstname:Universidad Tecnológica Indoaméricainstacron:UTI2024-11-07T14:45:19Zoai:repositorio.uti.edu.ec:20.500.14809/6916Institucionalhttps://repositorio.uti.edu.ec/Institución privadahttps://indoamerica.edu.ec/https://repositorio.uti.edu.ec/oai.Ecuador...opendoar:02024-11-07T14:45:19Repositorio Universidad Tecnológica Indoamérica - Universidad Tecnológica Indoaméricafalse |
| spellingShingle | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model Sánchez-Real, Emily |
| status_str | publishedVersion |
| title | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| title_full | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| title_fullStr | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| title_full_unstemmed | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| title_short | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| title_sort | Biomechanical Study of the Eye with Keratoconus-Type Corneal Ectasia Using a 3D Geometric Model |
| url | https://www.mdpi.com/2076-3417/13/22/12308 https://hdl.handle.net/20.500.14809/6916 |