Farmacovigilancia en hipertensos adultos mayores administrando amlodipino de 10 mg atendidos en el Hospital Maria Lorena Serrano Aguilar.

The present work was developed with the objective of evaluating the pharmacovigilance in elderly used as treatment for hypertension amlodipine 10 mg in the Hospital Maria Lorena Serrano Aguilar of El Guabo canton. The theory of reference was based on pharmacovigilance, it is depended on the eve of the medication that was consumed by the patient, where verified is the compliance of therapeutic function and the presence or absence of effects either adverse or side. To do this research method was used retrospective, prospective follow-up study, carried out in older adults with hypertension which was developed in a given time period is from October 2016 to June 2017, therefore; this study is experimental longitudinal (retrospective- prospective), in which the investigator intervenes and assess the effect on a number of interventions. Data and information was collected through the revision of clinical histories of patients with hypertension older adults, pharmacotherapy follow-up, in the same way it was evidenced the presence of suspected RAM through a therapeutic monitoring and the pharmaceutical care through the information that is given to the patients related to compliance with the specific treatment, to enhance your lifestyle and that the medication meets the expected effect without any adverse effect. According to the data were obtained more patients with hypertension in a range of 65 to 75 years, while in the genre there is more quantify of hypertensive women that have been presented at the Hospital Maria Lorena Serrano Aguilar, due to longer life expectancy in most populations, also managed to bring together information from the surveys along with the clinical histories claiming 16 cases of RAM between them are pains. It was evidenced the presence of some suspicions of RAM through the revision of clinical histories of the patients that used as treatment Amlodipine, where only 16% of the patients presented such suspicions being the most relevant pains therefore these are conducted a pharmacotherapy follow-up. It showed that of the 59 patients who were applied the pharmacovigilance, 16 patients had suspicions of RAM, therefore 42 patients rated the safety of the drug as safe and effective. Therefore being amlodipine used mostly in elderly patients for the treatment of hypertension, which at the present time already are sensitive to the effects of the drug, so we must be extremely cautious at the time that the medication is administered, especially when patients with chronic non-communicable diseases such as renal or hepatic dysfunction, among others, because they can be organic damage affecting the pharmacokinetics of the drug. Finally, it is recommended that the patient should follow the instructions that are written in the prescription, to achieve effective treatments, as well as must bear responsibility for the correct use of the medication, follow a proper diet and lead a better quality of life.

• Main Author: Aguilar Palma, Katherine Juleysi (author)
• Other Authors: Ruilova Maldonado, Marlon Andres (author)
• Format: bachelorThesis
• Published: 2017
• Subjects: ANTIHIPERTENSIVOS; EFECTOS SECUNDARIOS; HIPERTENSION; REACCIONES ADVERSAS, SEGUIMIENTO FARMACOTERAPÉUTICO.
• Online Access: http://repositorio.utmachala.edu.ec/handle/48000/11431