Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador

The MeOH extract of Piper ecuadorense Sodiro, Piperaceae, was chosen for metabolite isolation and elucidation due to the strong antifungal activity exhibited, measured by means of the broth microdilution method. Two known flavonoids: pinostrobin (1) and pinocembrin (2) were isolated from 4,16 g. of...

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Glavni avtor: Malagon Aviles, O. (author)
Drugi avtorji: Ramirez Robles, J. (author), Aguilar Ramirez, S. (author), Cartuche Flores, L. (author), Morocho Zaragocin, S. (author)
Format: article
Izdano: 2012
Teme:
Online dostop:http://dx.doi.org/10.1590/S0102-695X2013005000012
http://dspace.utpl.edu.ec/handle/123456789/19241
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author Malagon Aviles, O.
author2 Ramirez Robles, J.
Aguilar Ramirez, S.
Cartuche Flores, L.
Morocho Zaragocin, S.
author2_role author
author
author
author
author_facet Malagon Aviles, O.
Ramirez Robles, J.
Aguilar Ramirez, S.
Cartuche Flores, L.
Morocho Zaragocin, S.
author_role author
collection Repositorio Universidad Técnica Particular de Loja
dc.creator.none.fl_str_mv Malagon Aviles, O.
Ramirez Robles, J.
Aguilar Ramirez, S.
Cartuche Flores, L.
Morocho Zaragocin, S.
dc.date.none.fl_str_mv 2012-11-27
2017-06-16T22:03:11Z
2017-06-16T22:03:11Z
30/04/2013
dc.identifier.none.fl_str_mv http://dx.doi.org/10.1590/S0102-695X2013005000012
0102-695X
http://dx.doi.org/10.1590/S0102-695X2013005000012
http://dspace.utpl.edu.ec/handle/123456789/19241
dc.language.none.fl_str_mv Inglés
dc.publisher.none.fl_str_mv Brazilian Journal of Pharmacognosy
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.source.none.fl_str_mv reponame:Repositorio Universidad Técnica Particular de Loja
instname:Universidad Técnica Particular de Loja
instacron:UTPL
dc.subject.none.fl_str_mv antifungal activity
flavonoids
pinocembrin
pinostrobin
piper ecuadorense
matico de monte
dc.title.none.fl_str_mv Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
description The MeOH extract of Piper ecuadorense Sodiro, Piperaceae, was chosen for metabolite isolation and elucidation due to the strong antifungal activity exhibited, measured by means of the broth microdilution method. Two known flavonoids: pinostrobin (1) and pinocembrin (2) were isolated from 4,16 g. of dichloromethane extract by column chromatography, using a gradient of hexane/EtOAc. A total of 20 mg of 1 were obtained from the fraction eluted with hexane-EtOAc 95:5 v/v, and 100 mg of 2 were obtained from the fraction eluted with hexane-EtOAc 85:15 v/v. The MIC values of the MeOH extract was 31,25 �
eu_rights_str_mv openAccess
format article
id UTPL_5665ca1d51c8f4e6a20a3fa479fd6abf
identifier_str_mv 0102-695X
instacron_str UTPL
institution UTPL
instname_str Universidad Técnica Particular de Loja
language_invalid_str_mv Inglés
network_acronym_str UTPL
network_name_str Repositorio Universidad Técnica Particular de Loja
oai_identifier_str oai:dspace.utpl.edu.ec:123456789/19241
publishDate 2012
publisher.none.fl_str_mv Brazilian Journal of Pharmacognosy
reponame_str Repositorio Universidad Técnica Particular de Loja
repository.mail.fl_str_mv .
repository.name.fl_str_mv Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Loja
repository_id_str 1227
spelling Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from EcuadorMalagon Aviles, O.Ramirez Robles, J.Aguilar Ramirez, S.Cartuche Flores, L.Morocho Zaragocin, S.antifungal activityflavonoidspinocembrinpinostrobinpiper ecuadorensematico de monteThe MeOH extract of Piper ecuadorense Sodiro, Piperaceae, was chosen for metabolite isolation and elucidation due to the strong antifungal activity exhibited, measured by means of the broth microdilution method. Two known flavonoids: pinostrobin (1) and pinocembrin (2) were isolated from 4,16 g. of dichloromethane extract by column chromatography, using a gradient of hexane/EtOAc. A total of 20 mg of 1 were obtained from the fraction eluted with hexane-EtOAc 95:5 v/v, and 100 mg of 2 were obtained from the fraction eluted with hexane-EtOAc 85:15 v/v. The MIC values of the MeOH extract was 31,25 �Brazilian Journal of Pharmacognosy2017-06-16T22:03:11Z2012-11-272017-06-16T22:03:11Z30/04/2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1590/S0102-695X20130050000120102-695Xhttp://dx.doi.org/10.1590/S0102-695X2013005000012http://dspace.utpl.edu.ec/handle/123456789/19241Inglésinfo:eu-repo/semantics/openAccessreponame:Repositorio Universidad Técnica Particular de Lojainstname:Universidad Técnica Particular de Lojainstacron:UTPL2017-06-16T22:03:11Zoai:dspace.utpl.edu.ec:123456789/19241Institucionalhttps://dspace.utpl.edu.ec/Institución privadahttps://www.utpl.edu.ec/https://dspace.utpl.edu.ec/oai.Ecuador...opendoar:12272017-06-16T22:03:11Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Lojafalse
spellingShingle Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
Malagon Aviles, O.
antifungal activity
flavonoids
pinocembrin
pinostrobin
piper ecuadorense
matico de monte
status_str publishedVersion
title Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
title_full Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
title_fullStr Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
title_full_unstemmed Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
title_short Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
title_sort Antifungal activity of raw extract and flavanons isolated from Piper ecuadorense from Ecuador
topic antifungal activity
flavonoids
pinocembrin
pinostrobin
piper ecuadorense
matico de monte
url http://dx.doi.org/10.1590/S0102-695X2013005000012
http://dspace.utpl.edu.ec/handle/123456789/19241