Berberine, an epiphany against cancer
Alkaloids are used in traditional medicine for the treatment of many diseases. These compounds are synthesized in plants as secondary metabolites and have multiple effects on cellular metabolism. Among plant derivatives with biological properties, the isoquinoline quaternary alkaloid berberine posse...
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| Định dạng: | article |
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2017
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| Những chủ đề: | |
| Truy cập trực tuyến: | http://dx.doi.org/10.3390/molecules190812349 http://dspace.utpl.edu.ec/handle/123456789/19091 |
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Thêm thẻ | _version_ | 1862805029830787072 |
|---|---|
| author | Guaman Ortiz, L. |
| author_facet | Guaman Ortiz, L. |
| author_role | author |
| collection | Repositorio Universidad Técnica Particular de Loja |
| dc.creator.none.fl_str_mv | Guaman Ortiz, L. |
| dc.date.none.fl_str_mv | 01/08/2014 2017-06-16T22:02:55Z 2017-06-16T22:02:55Z |
| dc.identifier.none.fl_str_mv | http://dx.doi.org/10.3390/molecules190812349 14203049 http://dx.doi.org/10.3390/molecules190812349 http://dspace.utpl.edu.ec/handle/123456789/19091 |
| dc.language.none.fl_str_mv | Inglés |
| dc.publisher.none.fl_str_mv | Molecules |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio Universidad Técnica Particular de Loja instname:Universidad Técnica Particular de Loja instacron:UTPL |
| dc.subject.none.fl_str_mv | apoptosis autophagy berberine cancer traditional medicine |
| dc.title.none.fl_str_mv | Berberine, an epiphany against cancer |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Alkaloids are used in traditional medicine for the treatment of many diseases. These compounds are synthesized in plants as secondary metabolites and have multiple effects on cellular metabolism. Among plant derivatives with biological properties, the isoquinoline quaternary alkaloid berberine possesses a broad range of therapeutic uses against several diseases. In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. Based on this evidence, many derivatives have been synthesized to improve berberine efficiency and selectivity; the results so far obtained on human cancer cell lines support the idea that they could be promising agents for cancer treatment. The main properties of berberine and derivatives will be illustrated. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UTPL_9db59d612a84c667936b3260c480d2f7 |
| identifier_str_mv | 14203049 |
| instacron_str | UTPL |
| institution | UTPL |
| instname_str | Universidad Técnica Particular de Loja |
| language_invalid_str_mv | Inglés |
| network_acronym_str | UTPL |
| network_name_str | Repositorio Universidad Técnica Particular de Loja |
| oai_identifier_str | oai:dspace.utpl.edu.ec:123456789/19091 |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Molecules |
| reponame_str | Repositorio Universidad Técnica Particular de Loja |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Loja |
| repository_id_str | 1227 |
| spelling | Berberine, an epiphany against cancerGuaman Ortiz, L.apoptosisautophagyberberinecancertraditional medicineAlkaloids are used in traditional medicine for the treatment of many diseases. These compounds are synthesized in plants as secondary metabolites and have multiple effects on cellular metabolism. Among plant derivatives with biological properties, the isoquinoline quaternary alkaloid berberine possesses a broad range of therapeutic uses against several diseases. In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. Based on this evidence, many derivatives have been synthesized to improve berberine efficiency and selectivity; the results so far obtained on human cancer cell lines support the idea that they could be promising agents for cancer treatment. The main properties of berberine and derivatives will be illustrated.Molecules2017-06-16T22:02:55Z2017-06-16T22:02:55Z01/08/2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/molecules19081234914203049http://dx.doi.org/10.3390/molecules190812349http://dspace.utpl.edu.ec/handle/123456789/19091Inglésinfo:eu-repo/semantics/openAccessreponame:Repositorio Universidad Técnica Particular de Lojainstname:Universidad Técnica Particular de Lojainstacron:UTPL2017-06-16T22:02:55Zoai:dspace.utpl.edu.ec:123456789/19091Institucionalhttps://dspace.utpl.edu.ec/Institución privadahttps://www.utpl.edu.ec/https://dspace.utpl.edu.ec/oai.Ecuador...opendoar:12272017-06-16T22:02:55Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Lojafalse |
| spellingShingle | Berberine, an epiphany against cancer Guaman Ortiz, L. apoptosis autophagy berberine cancer traditional medicine |
| status_str | publishedVersion |
| title | Berberine, an epiphany against cancer |
| title_full | Berberine, an epiphany against cancer |
| title_fullStr | Berberine, an epiphany against cancer |
| title_full_unstemmed | Berberine, an epiphany against cancer |
| title_short | Berberine, an epiphany against cancer |
| title_sort | Berberine, an epiphany against cancer |
| topic | apoptosis autophagy berberine cancer traditional medicine |
| url | http://dx.doi.org/10.3390/molecules190812349 http://dspace.utpl.edu.ec/handle/123456789/19091 |