Development of anticancer drugs based on the hallmarks of tumor cells
Cancer remains a public health problem with a high unmet medical demand. However, in recent decades, the knowledge of several functional molecular and biological traits that distinguish tumor cells from normal cells, known as the hallmarks of cancer as described by Hannahan and Weinberg, has led to...
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| Формат: | article |
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2014
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| Нөхцлүүд: | |
| Онлайн хандалт: | http://dspace.utpl.edu.ec/handle/123456789/19172 |
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Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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Шошго нэмэх | _version_ | 1858364505518505984 |
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| author | Bailon Moscoso, N. |
| author2 | Romero Benavides, J. |
| author2_role | author |
| author_facet | Bailon Moscoso, N. Romero Benavides, J. |
| author_role | author |
| collection | Repositorio Universidad Técnica Particular de Loja |
| dc.creator.none.fl_str_mv | Bailon Moscoso, N. Romero Benavides, J. |
| dc.date.none.fl_str_mv | 2014-01-01 2017-06-16T22:03:04Z 2017-06-16T22:03:04Z 28/02/2014 |
| dc.identifier.none.fl_str_mv | 10.1007/s13277-014-1649-y 10104283 10.1007/s13277-014-1649-y http://dspace.utpl.edu.ec/handle/123456789/19172 |
| dc.language.none.fl_str_mv | Inglés |
| dc.publisher.none.fl_str_mv | Tumor Biology |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio Universidad Técnica Particular de Loja instname:Universidad Técnica Particular de Loja instacron:UTPL |
| dc.subject.none.fl_str_mv | Cancer Cancer cell hallmarks Drug design |
| dc.title.none.fl_str_mv | Development of anticancer drugs based on the hallmarks of tumor cells |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
| description | Cancer remains a public health problem with a high unmet medical demand. However, in recent decades, the knowledge of several functional molecular and biological traits that distinguish tumor cells from normal cells, known as the hallmarks of cancer as described by Hannahan and Weinberg, has led to new and modern therapeutic approaches against this disease. Most cancer drugs are deliberately developed for specific molecular targets that involve these hallmarks. In this review, we address the currently available cancer drugs and development of new drugs from the perspective of their interaction with these hallmarks as well as the pathways and mechanisms involved. © 2014 International Society of Oncology and BioMarkers (ISOBM). |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UTPL_d8b63d571b1d3ded0fcf9ee8eaf44bed |
| identifier_str_mv | 10.1007/s13277-014-1649-y 10104283 |
| instacron_str | UTPL |
| institution | UTPL |
| instname_str | Universidad Técnica Particular de Loja |
| language_invalid_str_mv | Inglés |
| network_acronym_str | UTPL |
| network_name_str | Repositorio Universidad Técnica Particular de Loja |
| oai_identifier_str | oai:dspace.utpl.edu.ec:123456789/19172 |
| publishDate | 2014 |
| publisher.none.fl_str_mv | Tumor Biology |
| reponame_str | Repositorio Universidad Técnica Particular de Loja |
| repository.mail.fl_str_mv | . |
| repository.name.fl_str_mv | Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Loja |
| repository_id_str | 1227 |
| spelling | Development of anticancer drugs based on the hallmarks of tumor cellsBailon Moscoso, N.Romero Benavides, J.CancerCancer cell hallmarksDrug designCancer remains a public health problem with a high unmet medical demand. However, in recent decades, the knowledge of several functional molecular and biological traits that distinguish tumor cells from normal cells, known as the hallmarks of cancer as described by Hannahan and Weinberg, has led to new and modern therapeutic approaches against this disease. Most cancer drugs are deliberately developed for specific molecular targets that involve these hallmarks. In this review, we address the currently available cancer drugs and development of new drugs from the perspective of their interaction with these hallmarks as well as the pathways and mechanisms involved. © 2014 International Society of Oncology and BioMarkers (ISOBM).Tumor Biology2017-06-16T22:03:04Z2017-06-16T22:03:04Z2014-01-0128/02/2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10.1007/s13277-014-1649-y1010428310.1007/s13277-014-1649-yhttp://dspace.utpl.edu.ec/handle/123456789/19172Inglésinfo:eu-repo/semantics/openAccessreponame:Repositorio Universidad Técnica Particular de Lojainstname:Universidad Técnica Particular de Lojainstacron:UTPL2017-06-16T22:03:04Zoai:dspace.utpl.edu.ec:123456789/19172Institucionalhttps://dspace.utpl.edu.ec/Institución privadahttps://www.utpl.edu.ec/https://dspace.utpl.edu.ec/oai.Ecuador...opendoar:12272017-06-16T22:03:04Repositorio Universidad Técnica Particular de Loja - Universidad Técnica Particular de Lojafalse |
| spellingShingle | Development of anticancer drugs based on the hallmarks of tumor cells Bailon Moscoso, N. Cancer Cancer cell hallmarks Drug design |
| status_str | publishedVersion |
| title | Development of anticancer drugs based on the hallmarks of tumor cells |
| title_full | Development of anticancer drugs based on the hallmarks of tumor cells |
| title_fullStr | Development of anticancer drugs based on the hallmarks of tumor cells |
| title_full_unstemmed | Development of anticancer drugs based on the hallmarks of tumor cells |
| title_short | Development of anticancer drugs based on the hallmarks of tumor cells |
| title_sort | Development of anticancer drugs based on the hallmarks of tumor cells |
| topic | Cancer Cancer cell hallmarks Drug design |
| url | http://dspace.utpl.edu.ec/handle/123456789/19172 |