Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes

Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. The interaction between 13-phenylalkyl and 13-diphenylalkyl berberine derivatives (NAX) and human telomeric DNA G4 structures has been investigated by both spectroscopic and crystallographic methods. NAX042 and NAX053 are the best compounds impr...

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Dettagli Bibliografici
Autore principale: Guaman Ortiz, L. (author)
Natura: article
Pubblicazione: 2016
Soggetti:
Alkaloids
Berberine
Crystal structure
G-quadruplexes
Telomeric DNA
X-ray diffraction
Accesso online:http://dspace.utpl.edu.ec/handle/123456789/18865
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