Design, construction of a low-cost hyperthermia equipment and validation with Magnetic Nanoparticles

In this thesis project, a low-cost induction heater was designed and built to aid in treating hyperthermia. During the construction process, the equipment was subjected to meticulous design adjustments to meet specific requirements. The results showed that the equipment had stable alternating current input, stable frequency oscillations in the medium frequency range, which is very suitable for the hyperthermia process, and efficient temperature control. To validate the equipment, ferrimagnetic and paramagnetic nanoparticles (magnetite and hematite) were mixed with simulated body fluid to simulate the fluid in a living body. The analysis of the temperature-time curves of Magnetic Nanoparticles (MNPs) under the influence of the electromagnetic field generated by the induction heater showed notable temperature increases, proving the effectiveness and reliability of the device for applications involving hyperthermia. Overall, this research provides a low-cost way to study the effect of magnetic nanoparticles on hyperthermia by combining magnetic nanoparticles with induction heating technology. By providing focused, non-invasive heating, the recently designed and constructed induction heater can enhance the study of an alternative method to treat cancer and present a competitive option to expensive, complex hyperthermia technology.

• Autore principale: Cevallos Benalcázar, Jordy Steve (author)
• Natura: bachelorThesis
• Lingua: eng
• Pubblicazione: 2024
• Soggetti: Dominios magnéticos; Histéresis; Magnetización; Magnetic domains; Hysteresis; Magnetization
• Accesso online: http://repositorio.yachaytech.edu.ec/handle/123456789/791