Evaluation of the antimicrobial properties of cellulose extracted from ecuadorian plants
The development of biomaterials is highly relevant in society due to the impact and benefit that it causes in some fields such as tissue engineering, synthetic biology, and biomedical devices. However, a significant problem in developing materials is the increasing incidence of resistant bacterial i...
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| Format: | bachelorThesis |
| Sprache: | eng |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | http://repositorio.yachaytech.edu.ec/handle/123456789/328 |
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Tag hinzufügen | Zusammenfassung: | The development of biomaterials is highly relevant in society due to the impact and benefit that it causes in some fields such as tissue engineering, synthetic biology, and biomedical devices. However, a significant problem in developing materials is the increasing incidence of resistant bacterial infections and the control of these micro-organisms' growth since these can both degrade the biomaterial and cause damage to the organism causing severe diseases. For that reason, it is necessary to search for new antimicrobial agents or coatings capable of preventing material surfaces from colonization by micro-organisms. A potential alternative to deal with this issue is natural plant biopolymers due to their low cost, availability, non-toxicity, and biodegradable properties. The present study will focus on testing different cellulose particles extracted from some Ecuadorian plants to identify if these biopolymers have antimicrobial properties. Thus, the project's objectives are to obtain cellulose particles from different sources using an established chemical extraction protocol, their characterization using known techniques, and the analysis of the antimicrobial properties of the cellulose through tests for inhibition of bacterial growth. The results showed that the bacterial growth rate with seven of the nine cellulose particles was lower than the negative control (without antibiotic). Significantly, the rates of bacterial growth with cellulose F1 and F53 were similar to the positive control (with antibiotic) with both strains of Escherichia coli ATCC25922 and TG1; hence they could have an inhibitory potential for surface-modified cellulosic materials applications in the future. |
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