Genetic Characterization Of Beta-Casein, Kappa-Casein And Beta-Lactoglobulin

There are 24 molecular markers or genes associated with essential milk traits for the production of dairy. Three of those molecular markers are CSN2, CSN3, and LGB. CSN2 has two common alleles, namely A1 and A2. In the Gastrointestinal digestion of the A1 monomers release a bioactive peptide, beta casomorphin-7 (BCM-7). BCM-7 is an opioid peptide plays a role in several human diseases and milk intolerance. BCM-7, derived from A1 beta-casein, has been linked is linked as a prevalence factor of diabetes, autism, autoimmune disease and others. On the other hand, the beta-casein A2 does not release BCM-7 because beta-casein A2 is more stable than A1. CSN3 is implicated in the micelle formation, and therefore in milk coagulation, which are fundamental characteristics for dairy production. Some studies have shown that the BB CSN3 variant has a faster and firmer gelling ability, which is essential in the production of dairy. LGB is associated with fat, protein, and casein content, which is fundamental in cheese yield. The research project aim was determining the genotype frequency of these three genes in four dairy cattle herds by different molecular biology techniques.

• Auteur principal: Laglaguano Morocho, Juan Carlos (author)
• Format: bachelorThesis
• Langue: eng
• Publié: 2020
• Sujets: Beta-caseín; Kappa-caseín; Beta-lactoglobulin; Genetic polimorphism; Beta caseína; Kappa caseína; Beta lactoglobulina; Polimorfismo genético
• Accès en ligne: http://repositorio.yachaytech.edu.ec/handle/123456789/190