Retrospective group study of risk factors for developing excessive erythrocytosis on the ecuadorian population living in the Sierra Region

Living at high altitude is related to the development of adaptive mechanisms in humans, high altitude (HA) diseases occur in areas greater than 2.500 m.a.s.l. where oxygen levels decrease to 75% in relation to sea level. This O2 deficiency causes an activation of chain mechanisms for adaptability to the environment. Millions of people around the world live at HA and can develop diseases due to a malfunction of the body, mainly caused by hypoxia, among these are chronic mountain disease (CMS) and excessive erythrocytosis (EE). The Andean population does not assimilate hypoxia induced by HA as do other mountaineers around the world (e.g. Tibetans). Appropriate medical information from EE is necessary to provide proper diagnosis and medical care for high-altitude people. The objective of this project is to investigate the risk factors for the development of EE based on the degree of HA. Taking this into consideration, two groups of patients will be examined, each of them inhabitants of different altitude regions (2.800 - 3.200 m medium HA (NA); and > 3.600 m HA) who will be scrutinized for the following selected variables: demography (sex, age and weight); health status variables (vital signs) and blood count variables (hematology). Cramer’s V statistical analysis, simple and multiple logistic regression will be carried out to reveal the presumed risk factors that sustain the EE.

• Huvudupphovsman: Pozo Parra, David Israel (author)
• Materialtyp: bachelorThesis
• Språk: eng
• Publicerad: 2021
• Ämnen: Eritrocitosis Excesiva (EE); Hemoglobina; Gran-altura; Andino; Excessive Erythrocytosis (EE); Hemoglobin; High-altitude; Andean
• Länkar: http://repositorio.yachaytech.edu.ec/handle/123456789/395