Identification of key amino acid residues toward improving the catalytic activity and substrate specificity of plant-derived cytochrome P450 monooxygenases CYP716A subfamily enzyme for triterpenoid production in Saccharomyces cerevisiae

Triterpenoids constitute a group of specialized plant metabolites with wide structural diversity and high therapeutic value for human health. Cytochrome P450 monooxygenases (CYP) are a family of enzymes important for generating the structural diversity of triterpenoids by catalyzing the site-specifi...

• Autore principale: Romsuk, Jutapat (author)
• Altri autori: Seki, Hikaru (author), Yasumoto, Shuhei (author), Fukushima, Ery Odette (author), Muranaka, Toshiya (author)
• Natura: article
• Pubblicazione: 2022
• Soggetti: Triterpene oxidase; Protein engineering; Bioinformatics,; In vivo functional analysis; Cytochrome P450 monooxygenase,; CYP716A
• Accesso online: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/602