Dissection of phospholipases A2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria

Cationic peptides bio-inspired by natural toxins have been recognized as an efficient strategy for the treatment of different health problems. Due to the specific interaction with substrates from biological membranes, snake venom phospholipases (PLA2s) represent valuable scaffolds for the research a...

• Autore principale: Peña Carrillo, María Sol (author)
• Altri autori: Pinos Tamayo, Edgar Alejandro (author), Mendes, Bruno (author), Domínguez Borbor, Cristobal (author), Proaño Bolaños, Carolina (author), Miguel, Danilo C. (author), de Almeida, José R. (author)
• Natura: article
• Pubblicazione: 2021
• Soggetti: Antimicrobial; Cationic; Leishmanicidal activity; Snake venom; Cytotoxicity
• Accesso online: https://doi.org/10.1016/j.bioorg.2021.105041; http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/451