Dissection of phospholipases A2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria

Dissection of phospholipases A2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria

Cationic peptides bio-inspired by natural toxins have been recognized as an efficient strategy for the treatment of different health problems. Due to the specific interaction with substrates from biological membranes, snake venom phospholipases (PLA2s) represent valuable scaffolds for the research a...

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Bibliographic Details
Main Author: Peña Carrillo, María Sol (author)
Other Authors: Pinos Tamayo, Edgar Alejandro (author), Mendes, Bruno (author), Domínguez Borbor, Cristobal (author), Proaño Bolaños, Carolina (author), Miguel, Danilo C. (author), de Almeida, José R. (author)
Format: article
Published: 2021
Subjects:
Antimicrobial
Cationic
Leishmanicidal activity
Snake venom
Cytotoxicity
Online Access:https://doi.org/10.1016/j.bioorg.2021.105041
http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/451
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