Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents

Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as structural models for the design of small peptides with anticancer, antibacterial and antiparasitic properties. Oligoarginine peptides are capable of increasing cell membrane permeability (cell penetratin...

• Huvudupphovsman: Mendes, Bruno (author)
• Övriga upphovsmän: de Almeida, José R. (author), Nuno Valec, Nuno (author), Gomese, Paula (author), Gadelhaf, Fernanda R. (author), da Silva, Saulo L. (author), Miguel, Danilo C. (author)
• Materialtyp: article
• Publicerad: 2019
• Ämnen: Leishmanicidal activity; Oligoarginine; Peptide; Phospholipase
• Länkar: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/316; https://doi.org/10.1016/j.cbpc.2019.108612