Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents

Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as structural models for the design of small peptides with anticancer, antibacterial and antiparasitic properties. Oligoarginine peptides are capable of increasing cell membrane permeability (cell penetratin...

• मुख्य लेखक: Mendes, Bruno (author)
• अन्य लेखक: de Almeida, José R. (author), Nuno Valec, Nuno (author), Gomese, Paula (author), Gadelhaf, Fernanda R. (author), da Silva, Saulo L. (author), Miguel, Danilo C. (author)
• स्वरूप: article
• प्रकाशित: 2019
• विषय: Leishmanicidal activity; Oligoarginine; Peptide; Phospholipase
• ऑनलाइन पहुंच: http://repositorio.ikiam.edu.ec/jspui/handle/RD_IKIAM/316; https://doi.org/10.1016/j.cbpc.2019.108612